Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | CASP2 | P42575 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2195042 | 0.93 | SLC6A5 (0.47) | TSHRSLC6A5FAAHHDAC3HDAC1 | |
| SCHEMBL2197667 | 0.93 | SLC6A5 (0.47) | TSHRSLC6A5FAAHHDAC3HDAC1 | |
| SCHEMBL23813807 | 0.88 | ALDH1A1 (0.40) | TSHRTPSAB1SLC6A5ALDH1A1CASP2 | |
| SCHEMBL14198853 | 0.88 | SLC6A5 (0.49) | TSHRTPSAB1SLC6A5FAAHCA1 | |
| SCHEMBL11142780 | 0.86 | CA1 (0.47) | TSHRTPSAB1SLC6A5FAAHCA1 | |
| SCHEMBL20710352 | 0.86 | SLC6A5 (0.51) | TSHRSLC6A5ALDH1A1FAAHHDAC3 | |
| SCHEMBL10057792 | 0.86 | SLC6A5 (0.51) | TSHRSLC6A5ALDH1A1FAAHHDAC3 | |
| SCHEMBL12680340 | 0.84 | LMNA (0.52) | TSHRSLC6A5MAPTALDH1A1HDAC3 | |
| SCHEMBL38654455 | 0.83 | ALDH1A1 (0.42) | TSHRTPSAB1SLC6A5ALDH1A1CASP2 | |
| Hydrochloric Acid SCHEMBL31354695 | 0.83 | BLM (0.52) | TSHRSLC6A5MAPTALDH1A1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7067620-B2 | Antibacterial agents | THERAVANCE, INC. (US) | 2006-06-27 | — | — | US | disclosed |
| US-20050171010-A1 | NOVEL ANTIBACTERIAL AGENTS | CUMBERLAND PHARMACEUTICALS INC. | 2005-08-04 | — | — | US | disclosed |
| US-6518242-B1 | Derivatives of glycopeptide antibacterial agents | THERAVANCE, INC. | 2003-02-11 | — | — | US | disclosed |
| EP-1060189-A1 | DERIVATIVES OF GLYCOPEPTIDE ANTIBACTERIAL AGENTS | Advanced Medicine, Inc. (US) | 2000-12-20 | — | — | EP | disclosed |
| WO-1999042476-A1 | NOVEL ANTIBACTERIAL AGENTS | ADVANCED MEDICINE, INC. (US) | 1999-08-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171010-A1 | NOVEL ANTIBACTERIAL AGENTS | ENGASE, GALE, MGAM | TSHR 4026/4885TPSAB1 450/4885SLC6A5 3186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.