Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 3/20 | 0.50 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.42 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | CTRC | Q99895 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.40 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.40 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5892099 | 0.91 | NR1H2 (0.57) | NR1H2NR1H3ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL5073360 | 0.82 | NR1H2 (0.57) | NR1H2NR1H3ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL7064955 | 0.76 | PTGS2 (0.45) | ALDH1A1GSK3BMEN1KMT2AMAPT | |
| SCHEMBL14359498 | 0.75 | TDP1 (0.52) | NR1H2NR1H3ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL6095174 | 0.74 | GAA (0.44) | NR1H2NR1H3F2PLGELANE | |
| SCHEMBL14031439 | 0.74 | MAPT (0.49) | NR1H2NR1H3ALDH1A1F2PLG | |
| SCHEMBL6389495 | 0.72 | NR1H2 (0.60) | NR1H2NR1H3ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL14275468 | 0.72 | NR1H2 (0.48) | NR1H2NR1H3ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL28080839 | 0.72 | NR1H2 (0.68) | NR1H2NR1H3ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL5892106 | 0.72 | HSD11B1 (0.47) | NR1H2NR1H3F2PLGELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060843-B1 | Electroluminescent devices comprising diketopyrrolopyrroles | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2006-06-13 | — | — | US | disclosed |
| US-7001677-B2 | Electroluminescent devices comprising diketopyrrolopyrroles | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2006-02-21 | — | — | US | disclosed |
| US-20040009368-A1 | Electroluminescent devices comprising diketopyrrolopyrroles | OTANI JUNJI (JP) | 2004-01-15 | — | — | US | disclosed |
| US-20030187106-A1 | Red, organge color; photostability, heat resistance | MORETTI ROBERT (CH) | 2003-10-02 | — | — | US | disclosed |
| US-6603020-B1 | Exhibiting a red or orange fluorescence | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-08-05 | — | — | US | disclosed |
| EP-1329493-A2 | Electroluminescent devices comprising diketopyrrolopyrroles | Ciba SC Holding AG (CH) | 2003-07-23 | — | — | EP | disclosed |
| EP-1087005-A1 | Fluorescent diketopyrrolopyrroles | Ciba SC Holding AG (CH) | 2001-03-28 | — | — | EP | disclosed |
| EP-1087006-A1 | Electroluminescent devices comprising diketopyrrolopyrroles | Ciba SC Holding AG (CH) | 2001-03-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187106-A1 | Red, organge color; photostability, heat resistance | CBR1, CBR3, DPP8 | NR1H2 330/4885NR1H3 719/4885ALDH1A1 63/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.