Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | CTSG | P08311 | 1/20 | 0.43 |
| ▸ | CMA1 | P23946 | 1/20 | 0.43 |
| ▸ | CTRC | Q99895 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | RGS4 | P49798 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | MGLL | Q99685 | 2/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2456324 | 0.85 | FAAH (0.41) | GAAHTTNPSR1GPR55NR1H2 | |
| SCHEMBL5073360 | 0.84 | NR1H2 (0.57) | NPSR1KMT2ANR1H2NR1H3ELANE | |
| SCHEMBL15094146 | 0.84 | NR1H2 (0.40) | GAAHTTNPSR1GPR55KMT2A | |
| SCHEMBL5892099 | 0.81 | NR1H2 (0.57) | KMT2ANR1H2NR1H3ELANEF2 | |
| SCHEMBL5892102 | 0.79 | NPSR1 (0.34) | GAAHTTNPSR1GPR55KMT2A | |
| SCHEMBL5892106 | 0.77 | HSD11B1 (0.47) | KMT2ANR1H2NR1H3ELANEF2 | |
| SCHEMBL14031439 | 0.76 | MAPT (0.49) | NPSR1KMT2ANR1H2NR1H3ELANE | |
| SCHEMBL7070855 | 0.76 | RGS4 (0.52) | NPSR1KMT2ANR1H2NR1H3POLB | |
| SCHEMBL14275468 | 0.75 | NR1H2 (0.48) | NPSR1KMT2ANR1H2NR1H3ELANE | |
| SCHEMBL5892104 | 0.74 | NR1H2 (0.50) | KMT2ANR1H2NR1H3ELANEF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060843-B1 | Electroluminescent devices comprising diketopyrrolopyrroles | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2006-06-13 | — | — | US | disclosed |
| EP-1087006-B1 | Electroluminescent devices comprising diketopyrrolopyrroles | CIBA SC HOLDING AG (CH) | 2003-10-15 | — | — | EP | disclosed |
| EP-1329493-A2 | Electroluminescent devices comprising diketopyrrolopyrroles | Ciba SC Holding AG (CH) | 2003-07-23 | — | — | EP | disclosed |
| EP-1087006-A1 | Electroluminescent devices comprising diketopyrrolopyrroles | Ciba SC Holding AG (CH) | 2001-03-28 | — | — | EP | disclosed |