Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 10/20 | 0.57 |
| ▸ | PTPRA | P18433 | 1/20 | 0.52 |
| ▸ | AKT1 | P31749 | 1/20 | 0.51 |
| ▸ | CTSS | P25774 | 3/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.44 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.44 |
| ▸ | CCKAR | P32238 | 1/20 | 0.43 |
| ▸ | CCKBR | P32239 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1731562 | 0.89 | PTPN1 (0.52) | PTPN1PTPRACTSSCTSK | |
| SCHEMBL2184299 | 0.89 | PTPN1 (0.52) | PTPN1PTPRACTSSCTSK | |
| SCHEMBL1731564 | 0.89 | PTPN1 (0.52) | PTPN1PTPRACTSSCTSK | |
| SCHEMBL5893907 | 0.85 | PTPN1 (0.55) | PTPN1PTPRAAKT1CTSSCTSK | |
| SCHEMBL5893060 | 0.85 | PTPN1 (0.70) | PTPN1 | |
| SCHEMBL5893307 | 0.83 | PTPN1 (0.53) | PTPN1PTPRAAKT1CTSSCTSK | |
| SCHEMBL1730696 | 0.82 | SRC (0.47) | PTPN1PTPRACTSSCTSKCTSL | |
| SCHEMBL1732507 | 0.82 | SRC (0.47) | PTPN1PTPRACTSSCTSKCTSL | |
| SCHEMBL2186575 | 0.82 | PTPN1 (0.50) | PTPN1PTPRA | |
| SCHEMBL1732891 | 0.82 | PTPN1 (0.50) | PTPN1PTPRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7141596-B2 | Inhibitors of proteins that bind phosphorylated molecules | INCYTE CORPORATION (US) | 2006-11-28 | — | — | US | disclosed |
| US-20050272778-A1 | Inhibitors of proteins that bind phosphorylated molecules | INCYTE CORPORATION | 2005-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050272778-A1 | Inhibitors of proteins that bind phosphorylated molecules | PPP3CA, PPP5C, PPM1A | PTPN1 133/4885PTPRA 74/4885AKT1 369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.