Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfanilamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 16/20 | 0.94 |
| ▸ | CA9 | Q16790 | 14/20 | 0.94 |
| ▸ | CA1 | P00915 | 13/20 | 0.94 |
| ▸ | CA12 | O43570 | 12/20 | 0.94 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.94 |
| ▸ | CA7 | P43166 | 6/20 | 0.94 |
| ▸ | CA6 | P23280 | 4/20 | 0.94 |
| ▸ | CA5A | P35218 | 4/20 | 0.94 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.94 |
| ▸ | TSHR | P16473 | 3/20 | 0.94 |
| ▸ | CA4 | P22748 | 3/20 | 0.94 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.94 |
| ▸ | USP2 | O75604 | 1/20 | 0.94 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.94 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.94 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MPO | P05164 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfanilamide SCHEMBL7624621 | 1.00 | CA2 (0.94) | CA2CA9CA1CA12CA14 | |
| Sulfanilamide SCHEMBL740 | 0.97 | CA2 (1.00) | CA2CA9CA1CA12CA14 | |
| Sulfanilamide SCHEMBL2798899 | 0.97 | CA2 (1.00) | CA2CA9CA1CA12CA14 | |
| Sulfanilamide SCHEMBL31544839 | 0.97 | CA2 (1.00) | CA2CA9CA1CA12CA14 | |
| Sulfanilamide SCHEMBL30659052 | 0.97 | CA2 (1.00) | CA2CA9CA1CA12CA14 | |
| Sulfanilamide SCHEMBL8030126 | 0.94 | CA2 (0.94) | CA2CA9CA1CA12CA14 | |
| Sulfanilamide SCHEMBL22501553 | 0.94 | CA2 (0.94) | CA2CA9CA1CA12CA14 | |
| Sulfanilamide SCHEMBL19210078 | 0.94 | CA2 (0.94) | CA2CA9CA1CA12CA14 | |
| Sulfanilamide SCHEMBL3273308 | 0.94 | CA2 (0.94) | CA2CA9CA1CA12CA14 | |
| Sulfanilamide SCHEMBL1155220 | 0.94 | CA2 (0.94) | CA2CA9CA1CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118275363-A | Method and device for online measurement of concentration of atmospheric nitric acid | 中国科学院化学研究所 | 2024-07-02 | — | — | CN | claimed |
| CN-117105825-A | Synthesis method of celecoxib intermediate p-hydrazino benzenesulfonamide hydrochloride | 济南大学 | 2023-11-24 | — | — | CN | claimed |
| CN-116606231-A | P-sulfonamide phenylhydrazine hydrochloride and preparation method thereof | 河北冀衡药业股份有限公司 | 2023-08-18 | — | — | CN | claimed |
| CN-113218895-B | Detection system and method for determining total nitrogen content in water | 苏州微湃医疗科技有限公司 | 2023-04-07 | — | — | CN | claimed |
| CN-110872242-B | Synthesis method of celecoxib intermediate p-hydrazino benzenesulfonamide hydrochloride | 湖南方盛制药股份有限公司 | 2022-03-29 | — | — | CN | claimed |
| CN-109828089-B | DBN-BP-based water quality parameter nitrous acid nitrogen online prediction method | 仲恺农业工程学院 | 2022-01-18 | — | — | CN | claimed |
| CN-110183684-B | Modified oil shale semicoke, preparation method thereof and application thereof in high polymer material | 烟台佳合高分子材料有限公司 | 2021-10-15 | — | — | CN | claimed |
| CN-113336680-A | Environment-friendly technological synthesis method of sulfanilamide | 寿光永康化学工业有限公司 | 2021-09-03 | — | — | CN | claimed |
| CN-113218895-A | Detection system and method for determining total nitrogen content in water | 苏州微湃医疗科技有限公司 | 2021-08-06 | — | — | CN | claimed |
| CN-110872242-A | Synthesis method of celecoxib intermediate p-hydrazino benzenesulfonamide hydrochloride | 湖南方盛制药股份有限公司 | 2020-03-10 | — | — | CN | claimed |
| CN-105189506-A | Compounds and compositions for the treatment of parasitic diseases | NOVARTIS AG | 2015-12-23 | — | — | CN | claimed |
| JP-10218856-A | — | — | None | — | — | JP | disclosed |
| CN-116606231-B | P-sulfonamide phenylhydrazine hydrochloride and preparation method thereof | 河北冀衡药业股份有限公司 | 2025-08-12 | — | — | CN | disclosed |
| CN-118275363-A | Method and device for online measurement of concentration of atmospheric nitric acid | 中国科学院化学研究所 | 2024-07-02 | — | — | CN | disclosed |
| CN-117653788-A | Method for reducing calcification of bioprosthetic tissue and bioprosthetic tissue | 上海微创心通医疗科技有限公司 | 2024-03-08 | — | — | CN | disclosed |
| EP-1009738-A1 | SUBSTITUTED OXINDOLE DERIVATIVES AS PROTEIN TYROSINE KINASE AND AS PROTEIN SERINE/THREONINE KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2000-06-21 | — | — | EP | disclosed |
| WO-1999015500-A1 | SUBSTITUTED OXINDOLE DERIVATIVES AS PROTEIN TYROSINE KINASE AND AS PROTEIN SERINE/THREONINE KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 1999-04-01 | — | — | WO | disclosed |
| JP-H10218856-A | PRODUCTION OF 4-SULFONAMIDOPHENYLHYDRAZINE HYDROCHLORIDE | SUMIKA FINE CHEM KK | 1998-08-18 | — | — | JP | disclosed |
| EP-0196091-B1 | METHOD OF PROCESSING LIGHT-SENSITIVE SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL | KONICA CORPORATION (JP) | 1992-10-28 | — | — | EP | disclosed |
| US-4863837-A | Method of processing light-sensitive silver halide color photographic material comprising combinations of two different sequestering agents and a sensitizing dye | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1989-09-05 | — | — | US | disclosed |