Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfanilamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 17/20 | 0.94 |
| ▸ | CA9 | Q16790 | 16/20 | 0.94 |
| ▸ | CA12 | O43570 | 14/20 | 0.94 |
| ▸ | CA1 | P00915 | 14/20 | 0.94 |
| ▸ | CA14 | Q9ULX7 | 7/20 | 0.94 |
| ▸ | CA7 | P43166 | 7/20 | 0.94 |
| ▸ | CA6 | P23280 | 5/20 | 0.94 |
| ▸ | CA5A | P35218 | 5/20 | 0.94 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.94 |
| ▸ | CA4 | P22748 | 4/20 | 0.94 |
| ▸ | TSHR | P16473 | 3/20 | 0.94 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.94 |
| ▸ | USP2 | O75604 | 1/20 | 0.94 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.94 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.94 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MPO | P05164 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfanilamide SCHEMBL30659052 | 0.97 | CA2 (1.00) | CA2CA9CA12CA1CA14 | |
| Sulfanilamide SCHEMBL2798899 | 0.97 | CA2 (1.00) | CA2CA9CA12CA1CA14 | |
| Sulfanilamide SCHEMBL740 | 0.97 | CA2 (1.00) | CA2CA9CA12CA1CA14 | |
| Sulfanilamide SCHEMBL31544839 | 0.97 | CA2 (1.00) | CA2CA9CA12CA1CA14 | |
| Sulfanilamide SCHEMBL8828319 | 0.94 | CA2 (0.94) | CA2CA9CA12CA1CA14 | |
| Sulfanilamide SCHEMBL22501553 | 0.94 | CA2 (0.94) | CA2CA9CA12CA1CA14 | |
| Sulfanilamide SCHEMBL19210078 | 0.94 | CA2 (0.94) | CA2CA9CA12CA1CA14 | |
| Sulfanilamide SCHEMBL5894222 | 0.94 | CA2 (0.94) | CA2CA9CA12CA1CA14 | |
| Sulfanilamide SCHEMBL3273308 | 0.94 | CA2 (0.94) | CA2CA9CA12CA1CA14 | |
| Sulfanilamide SCHEMBL1155220 | 0.94 | CA2 (0.94) | CA2CA9CA12CA1CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5148876-A | — | — | None | — | — | JP | disclosed |
| CN-100439568-C | Method and device for processing mesh cloth | 3M INNOVATIVE PROPERTIES CO (US) | 2008-12-03 | — | — | CN | disclosed |
| CN-1646733-A | Web processing method and apparatus | 3M INNOVATIVE PROPERTIES CO (US) | 2005-07-27 | — | — | CN | disclosed |
| JP-2000212795-A | NICKEL PLATED HIGH CARBON STEEL WIRE FOR SPRING EXCELLENT IN CORROSION RESISTANCE | COURSE JAPAN:KK | 2000-08-02 | — | — | JP | disclosed |
| US-6030890-A | Method of manufacturing a semiconductor device | SONY CORPORATION (JP) | 2000-02-29 | — | — | US | disclosed |
| US-6008543-A | Conductive bumps on pads for flip chip application | SONY CORPORATION (JP) | 1999-12-28 | — | — | US | disclosed |
| EP-0681039-B1 | A titanium alloy engine valve shaft structure | FUJI VALVE (JP) | 1997-09-10 | — | — | EP | disclosed |
| EP-0681039-A1 | A titanium alloy engine valve shaft structure | FUJI OOZX INC. (JP) | 1995-11-08 | — | — | EP | disclosed |
| US-5370364-A | Nickel-phosphorus-fine ceramic coating layer; abrasiion and fatigue resistance | FUJI OOZX INC. (JP) | 1994-12-06 | — | — | US | disclosed |
| JP-H05148876-A | GARBAGE DISPOSER | MATSUSHITA ELECTRIC IND CO LTD | 1993-06-15 | — | — | JP | disclosed |
| US-4290857-A | Method of forming fine bore | RICOH CO., LTD. (JP) | 1981-09-22 | — | — | US | disclosed |