Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16790820 | 0.87 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1LMNAMAPTKMT2A | |
| SCHEMBL30436104 | 0.81 | ALOX15 (0.56) | ALDH1A1L3MBTL1LMNAMAPTKMT2A | |
| SCHEMBL14208295 | 0.81 | ALOX15 (0.56) | ALDH1A1L3MBTL1LMNAMAPTKMT2A | |
| SCHEMBL253780 | 0.81 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1LMNAMAPTKMT2A | |
| SCHEMBL31229683 | 0.80 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1LMNAMAPTKMT2A | |
| SCHEMBL10323118 | 0.80 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1LMNAMAPTKMT2A | |
| SCHEMBL590057 | 0.78 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1LMNAMAPTKMT2A | |
| SCHEMBL20589469 | 0.78 | SYK (0.52) | ALDH1A1L3MBTL1LMNAMAPTKMT2A | |
| SCHEMBL10322742 | 0.76 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1LMNAMAPTKMT2A | |
| SCHEMBL31422797 | 0.76 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1LMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9315499-B2 | Cytomegalovirus inhibitor compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-04-19 | — | — | US | disclosed |
| US-20150158861-A1 | CYTOMEGALOVIRUS INHIBITOR COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-06-11 | — | — | US | disclosed |
| US-8450243-B2 | Herbicidal quinoline and 1,8-naphthyridine compounds | SYNGENTA LIMITED (GB) | 2013-05-28 | — | — | US | disclosed |
| EP-2417132-B1 | HERBICIDAL QUINOLINE AND 1,8-NAPHTHYRIDINE COMPOUNDS | SYNGENTA LTD (GB) | 2013-04-17 | — | — | EP | disclosed |
| US-20120094833-A1 | HERBICIDAL QUINOLINE AND 1,8 -NAPHTHYRIDINE COMPOUNDS | SYNGENTA CROP PROTECTION, LLC (US) | 2012-04-19 | — | — | US | disclosed |
| EP-2417132-A2 | HERBICIDAL QUINOLINE AND 1,8-NAPHTHYRIDINE COMPOUNDS | Syngenta Limited (GB) | 2012-02-15 | — | — | EP | disclosed |
| WO-2010116122-A2 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2010-10-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150158861-A1 | CYTOMEGALOVIRUS INHIBITOR COMPOUNDS | CCNT1, CDKN1A, FOXM1 | ALDH1A1 3564/4885L3MBTL1 1216/4885LMNA 3610/4885 |
| US-20120094833-A1 | HERBICIDAL QUINOLINE AND 1,8 -NAPHTHYRIDINE COMPOUNDS | NQO2, QDPR, CYP4X1 | ALDH1A1 746/4885L3MBTL1 2891/4885LMNA 4058/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.