Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5894750 | 0.94 | KMT2A (0.36) | KMT2APKMTSHRTDP1ALDH1A1 | |
| SCHEMBL5894041 | 0.83 | PKM (0.36) | KMT2APKMIDO1TSHRTDP1 | |
| SCHEMBL5894356 | 0.82 | IDO1 (0.39) | IDO1ALDH1A1MAPT | |
| SCHEMBL5894601 | 0.78 | KEAP1 (0.36) | IDO1 | |
| SCHEMBL5894481 | 0.77 | KMT2A (0.35) | KMT2APKMTSHRTDP1ALDH1A1 | |
| SCHEMBL5894509 | 0.77 | PKM (0.33) | KMT2APKMTSHRTDP1ALDH1A1 | |
| SCHEMBL5894255 | 0.77 | PKM (0.33) | KMT2APKMTSHRTDP1ALDH1A1 | |
| SCHEMBL5894464 | 0.77 | MAPT (0.36) | KMT2APKMTSHRTDP1ALDH1A1 | |
| SCHEMBL5894543 | 0.76 | MAPT (0.36) | KMT2APKMTSHRTDP1MAPT | |
| SCHEMBL5894802 | 0.76 | MAPT (0.41) | KMT2APKMTSHRTDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060156485-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2006-07-20 | — | — | US | claimed |
| US-20060156485-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060156485-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | KRT18, TUBB6, DNMT1 | KMT2A 810/4885PKM 1496/4885IDO1 1240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.