Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5894841 | 0.85 | — | — | |
| SCHEMBL5894644 | 0.70 | ALDH1A1 (0.31) | ALDH1A1CYP3A4 | |
| SCHEMBL5894226 | 0.64 | GAA (0.35) | ALDH1A1CYP3A4GAAMAPTCA12 | |
| SCHEMBL5606122 | 0.63 | ALDH1A1 (0.46) | ALDH1A1CYP3A4GAAMAPTCA12 | |
| SCHEMBL5605839 | 0.63 | ALDH1A1 (0.46) | ALDH1A1CYP3A4GAAMAPTCA12 | |
| SCHEMBL5894313 | 0.63 | ALDH1A1 (0.34) | ALDH1A1CYP3A4GAAMAPTCA12 | |
| SCHEMBL13732876 | 0.61 | ALDH1A1 (0.44) | ALDH1A1CYP3A4GAAMAPTCA12 | |
| SCHEMBL5605453 | 0.61 | ALDH1A1 (0.44) | ALDH1A1CYP3A4GAAMAPTCA12 | |
| SCHEMBL5604970 | 0.61 | ALDH1A1 (0.44) | ALDH1A1CYP3A4GAAMAPTCA12 | |
| SCHEMBL5894621 | 0.61 | EP300 (0.38) | ALDH1A1GAAMAPTCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060156485-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2006-07-20 | — | — | US | claimed |
| US-20060156485-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060156485-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | KRT18, TUBB6, DNMT1 | ALDH1A1 385/4885CYP3A4 526/4885GAA 3519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.