Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.60 |
| ▸ | ITGA2B | P08514 | 14/20 | 0.60 |
| ▸ | HRAS | P01112 | 4/20 | 0.57 |
| ▸ | ESR1 | P03372 | 4/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.57 |
| ▸ | NHERF1 | O14745 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5889527 | 0.94 | HRAS (0.61) | ITGB3ITGA2BHRASESR1ESR2 | |
| SCHEMBL5677746 | 0.89 | ITGB3 (0.59) | ITGB3ITGA2BHRASESR1ESR2 | |
| SCHEMBL5897347 | 0.83 | ITGB3 (0.54) | ITGB3ITGA2BHRASESR1ESR2 | |
| SCHEMBL8205586 | 0.82 | NHERF1 (0.68) | NHERF1 | |
| SCHEMBL5677265 | 0.80 | ITGB3 (0.54) | ITGB3ITGA2BNHERF1 | |
| SCHEMBL5677297 | 0.80 | ITGB3 (0.64) | ITGB3ITGA2B | |
| SCHEMBL5680312 | 0.80 | NHERF1 (0.54) | ITGB3ITGA2BNHERF1 | |
| SCHEMBL5896843 | 0.78 | HTR2C (0.59) | ITGB3ITGA2BNHERF1 | |
| SCHEMBL5889622 | 0.78 | ITGB3 (0.53) | ITGB3ITGA2BHRASESR1ESR2 | |
| SCHEMBL5889839 | 0.77 | HDAC2 (0.56) | ITGB3ITGA2BNHERF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7141680-B2 | Aromatic compounds possessing antifungal or antibacterial activity | GENELABS TECHNOLOGIES, INC. | 2006-11-28 | — | — | US | claimed |
| US-7141680-B2 | Aromatic compounds possessing antifungal or antibacterial activity | GENELABS TECHNOLOGIES, INC. | 2006-11-28 | — | — | US | disclosed |