SCHEMBL589725

SCHEMBL589725

COC(=O)c1cc2ccccc2c(O)c1C(=O)OC

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59
MAPT P10636 1/20 0.59
ALDH1A1 P00352 3/20 0.59
HPGD P15428 3/20 0.59
KDM4E B2RXH2 3/20 0.59
NPSR1 Q6W5P4 1/20 0.59
PTPN1 P18031 1/20 0.49
MPL P40238 1/20 0.48
LMNA P02545 2/20 0.47
TSHR P16473 1/20 0.47
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
LCK P06239 1/20 0.45
NCEH1 Q6PIU2 1/20 0.44
SLC6A2 P23975 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11780209 0.87 ALDH1A1 (0.62) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL6501360 0.85 MEN1 (0.54) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL31667830 0.83 MEN1 (0.58) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL3926157 0.83 MEN1 (0.48) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL28283411 0.83 MEN1 (0.48) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL28217578 0.83 KDM4E (0.57) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL5083672 0.82 MAPT (0.83) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL6824108 0.81 MEN1 (0.63) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL10522616 0.80 MEN1 (0.59) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL6345805 0.80 MEN1 (0.43) MEN1KMT2AMAPTALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12163968-B2 Preparation of nucleated RBC (NRBC) analogs for use as reference hematology controls in automated hematology analyzers BIO-RAD LABORATORIES, INC. (US) 2024-12-10 US claimed
US-12163968-B2 Preparation of nucleated RBC (NRBC) analogs for use as reference hematology controls in automated hematology analyzers BIO-RAD LABORATORIES, INC. (US) 2024-12-10 US disclosed
EP-4208021-A1 PREPARATION OF NUCLEATED RBC (NRBC) ANALOGS FOR USE AS REFERENCE HEMATOLOGY CONTROLS IN AUTOMATED HEMATOLOGY ANALYZERS Bio-Rad Laboratories, Inc. (US) 2023-07-12 EP disclosed
CN-116097093-A Preparation of Nucleated RBC (NRBC) analogs for use as reference blood controls in automated blood analyzers 生物辐射实验室股份有限公司 2023-05-09 CN disclosed
WO-2022051443-A1 PREPARATION OF NUCLEATED RBC (NRBC) ANALOGS FOR USE AS REFERENCE HEMATOLOGY CONTROLS IN AUTOMATED HEMATOLOGY ANALYZERS BIO-RAD LABORATORIES, INC. (US) 2022-03-10 WO disclosed
US-20220065878-A1 PREPARATION OF NUCLEATED RBC (NRBC) ANALOGS FOR USE AS REFERENCE HEMATOLOGY CONTROLS IN AUTOMATED HEMATOLOGY ANALYZERS BIO-RAD LABORATORIES, INC. 2022-03-03 US disclosed
EP-2376908-B1 SIMULATION OF NORMAL FRESH BLOOD PLATELETS BIO RAD LABORATORIES (US) 2014-12-31 EP disclosed
CN-102341701-B Mimetics of normal fresh platelets BIO RAD LABORATORIES 2014-07-09 CN disclosed
US-8114580-B2 Simulation of normal fresh blood platelets for reference control BIO-RAD LABORATORIES, INC. (US) 2012-02-14 US disclosed
EP-2376908-A1 SIMULATION OF NORMAL FRESH BLOOD PLATELETS Bio-Rad Laboratories, Inc. (US) 2011-10-19 EP disclosed
WO-2010083130-A1 SIMULATION OF NORMAL FRESH BLOOD PLATELETS BIO-RAD LABORATORIES, INC. (US) 2010-07-22 WO disclosed
US-20100178647-A1 SIMULATION OF NORMAL FRESH BLOOD PLATELETS BIO-RAD LABORATORIES, INC. (US) 2010-07-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100178647-A1 SIMULATION OF NORMAL FRESH BLOOD PLATELETS MPL, THPO, PFKP MEN1 906/4885KMT2A 2601/4885MAPT 4876/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.