Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5897049 | 0.88 | POLB (0.54) | MAPTLMNANPSR1TAS1R3TAS1R1 | |
| SCHEMBL5896951 | 0.86 | NPSR1 (0.53) | MAPTLMNANPSR1TAS1R3TAS1R1 | |
| SCHEMBL5896874 | 0.82 | LMNA (0.49) | MAPTLMNANPSR1TAS1R3TAS1R1 | |
| SCHEMBL5896459 | 0.77 | ITGB1 (0.53) | MAPTLMNANPSR1KMT2AMEN1 | |
| SCHEMBL7876199 | 0.76 | HPGD (0.52) | MAPTLMNANPSR1TAS1R3TAS1R1 | |
| SCHEMBL20154292 | 0.76 | AAK1 (0.43) | MAPTTAS1R3TAS1R1KMT2AALDH1A1 | |
| SCHEMBL20154372 | 0.76 | AAK1 (0.43) | MAPTTAS1R3TAS1R1KMT2AALDH1A1 | |
| SCHEMBL20154293 | 0.76 | AAK1 (0.43) | MAPTTAS1R3TAS1R1KMT2AALDH1A1 | |
| SCHEMBL7876448 | 0.76 | POLB (0.58) | MAPTLMNANPSR1TAS1R3TAS1R1 | |
| SCHEMBL30594182 | 0.75 | NPC1 (0.40) | MAPTTAS1R3TAS1R1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7091242-B2 | Beta-amino acid derivatives as integrin receptor antagonists | BAYER AKTIENGESELLSCHAFT (DE) | 2006-08-15 | — | — | US | disclosed |
| US-20040058904-A1 | Beta-amino acid derivatives as integrin receptor antagonists | BAYER AKTIENGESELLSCHAFT (DE) | 2004-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058904-A1 | Beta-amino acid derivatives as integrin receptor antagonists | ITGAL, ITGB1, ITGB2 | MAPT 2980/4885LMNA 2349/4885NPSR1 344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.