Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.57 |
| ▸ | DNA2 | P51530 | 1/20 | 0.57 |
| ▸ | CASP6 | P55212 | 1/20 | 0.57 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.49 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | FBP1 | P09467 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4739348 | 0.91 | CLEC4M (0.71) | CLEC4MDNA2CASP6CTDSP1KDM4E | |
| SCHEMBL3245558 | 0.84 | CLEC4M (0.52) | CLEC4MDNA2CASP6CTDSP1KDM4E | |
| SCHEMBL3066032 | 0.81 | DNA2 (0.66) | DNA2CASP6CTDSP1ALDH1A1MAPT | |
| SCHEMBL1277854 | 0.81 | DNA2 (0.83) | DNA2CASP6CTDSP1KDM4EALDH1A1 | |
| SCHEMBL5752237 | 0.80 | ALDH1A1 (0.54) | CLEC4MKDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11329048 | 0.77 | ALDH1A1 (0.49) | CLEC4MALDH1A1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL6215533 | 0.77 | DNA2 (0.61) | DNA2CASP6CTDSP1KDM4EALDH1A1 | |
| SCHEMBL4728649 | 0.77 | ALDH1A1 (0.54) | ALDH1A1MAPTSMN1; SMN2MAPK1MEN1 | |
| SCHEMBL4135400 | 0.77 | THRB (0.55) | ALDH1A1MAPTSMN1; SMN2MAPK1MEN1 | |
| SCHEMBL3481205 | 0.76 | TSHR (0.64) | KDM4EALDH1A1MAPTSMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7141680-B2 | Aromatic compounds possessing antifungal or antibacterial activity | GENELABS TECHNOLOGIES, INC. | 2006-11-28 | — | — | US | disclosed |
| US-20040063645-A1 | Novel aromatic compounds possessing antifungal or antibacterial activity | SMITHKLINE BEECHAM CORPORATION | 2004-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063645-A1 | Novel aromatic compounds possessing antifungal or antibacterial activity | ZC3HAV1, TYR, ZC3HAV1L | CLEC4M 930/4885DNA2 807/4885CASP6 82/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.