Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5851890 | 0.82 | CA1 (0.42) | ALDH1A1MAPTRAB9ANPC1HTT | |
| Hydrochloric Acid SCHEMBL5852688 | 0.81 | CA1 (0.41) | ALDH1A1MAPTRAB9ANPC1HTT | |
| Hydrochloric Acid SCHEMBL589320 | 0.76 | KDM4A (0.42) | — | |
| SCHEMBL10206261 | 0.76 | PRMT6 (0.55) | MAPTPRMT6CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9943767 | 0.73 | DAO (0.44) | ALDH1A1MAPTRAB9ANPC1HTT | |
| SCHEMBL27969999 | 0.72 | MAOA (0.36) | ALDH1A1MAPTRAB9ANPC1CYP1A2 | |
| SCHEMBL14125885 | 0.71 | PRMT6 (0.37) | ALDH1A1MAPTPRMT6CYP2D6CYP2C9 | |
| SCHEMBL2329773 | 0.71 | — | — | |
| SCHEMBL25285311 | 0.70 | ALDH1A1 (0.37) | ALDH1A1MAPTRAB9ANPC1HTT | |
| SCHEMBL25278765 | 0.70 | ALDH1A1 (0.55) | ALDH1A1MAPTRAB9ANPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7125883-B1 | Integrin receptor ligands | ABBOTT GMBH & CO. KG (DE) | 2006-10-24 | — | — | US | disclosed |