Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 6/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879547 | 0.84 | KDM4E (0.61) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL10372053 | 0.78 | KMT2A (0.56) | MAPTL3MBTL1BRD4HPGDSMN1; SMN2 | |
| SCHEMBL7993458 | 0.77 | ALDH1A1 (0.56) | SMN1; SMN2 | |
| SCHEMBL11909187 | 0.75 | GRIN2B (0.43) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL10368749 | 0.74 | BRD4 (0.59) | MAPTL3MBTL1BRD4SMN1; SMN2 | |
| SCHEMBL17796145 | 0.74 | CXCR4 (0.48) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL9963676 | 0.73 | PPID (0.46) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL3991264 | 0.72 | KDM4E (0.57) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL3899220 | 0.72 | TDP1 (0.46) | BRD4TDP1 | |
| SCHEMBL6684742 | 0.71 | BRD4 (0.64) | MAPTL3MBTL1BRD4HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7125883-B1 | Integrin receptor ligands | ABBOTT GMBH & CO. KG (DE) | 2006-10-24 | — | — | US | disclosed |