Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.56 |
| ▸ | GLA | P06280 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2584410 | 0.88 | ALDH1A1 (0.65) | ALDH1A1ALOX12GLAKDM4ESMN1; SMN2 | |
| SCHEMBL8000757 | 0.84 | KDM4E (0.80) | ALDH1A1ALOX12GLAKDM4EPKM | |
| SCHEMBL7474517 | 0.84 | RAB9A (0.65) | ALDH1A1ALOX12GLAKDM4ESMN1; SMN2 | |
| SCHEMBL5123025 | 0.80 | NPC1 (0.60) | ALDH1A1ALOX12GLAKDM4ESMN1; SMN2 | |
| SCHEMBL5897576 | 0.77 | HDAC3 (0.52) | SMN1; SMN2 | |
| SCHEMBL6536256 | 0.76 | KDM4E (0.55) | KDM4EPKM | |
| SCHEMBL4290054 | 0.75 | NPC1 (0.66) | ALDH1A1ALOX12GLASMN1; SMN2MITF | |
| SCHEMBL7475623 | 0.75 | NPC1 (0.66) | ALDH1A1ALOX12GLASMN1; SMN2MITF | |
| SCHEMBL5392388 | 0.75 | ALDH1A1 (0.51) | ALDH1A1ALOX12GLAKDM4ESMN1; SMN2 | |
| SCHEMBL1594516 | 0.75 | ALDH1A1 (0.52) | ALDH1A1ALOX12GLAKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001064675-A1 | CONDENSED THIAZOLAMINES AND THEIR USE AS NEUROPEPTIDE Y5 ANTAGONISTS | NOVARTIS AG (CH) | 2001-09-07 | — | — | WO | disclosed |