Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6965437 | 0.90 | USP2 (0.64) | USP2MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL21838012 | 0.84 | USP2 (0.45) | USP2MTNR1B | |
| SCHEMBL21838015 | 0.84 | USP2 (0.45) | USP2MTNR1B | |
| SCHEMBL30278732 | 0.84 | USP2 (0.48) | USP2KMT2AMTNR1BPSEN1PSEN2 | |
| SCHEMBL9006395 | 0.81 | USP2 (0.65) | USP2MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL30861838 | 0.80 | USP2 (0.44) | USP2MAPTMTNR1BPSEN1PSEN2 | |
| SCHEMBL30278700 | 0.80 | USP2 (0.44) | USP2MAPTMTNR1BPSEN1PSEN2 | |
| SCHEMBL9536587 | 0.80 | USP2 (0.59) | USP2L3MBTL1MEN1KMT2ATSHR | |
| SCHEMBL9536593 | 0.80 | USP2 (0.59) | USP2L3MBTL1MEN1KMT2ATSHR | |
| SCHEMBL8978441 | 0.80 | USP2 (0.56) | USP2L3MBTL1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7026515-B2 | Optically active amine derivatives and preparation process therefor | MITSUI CHEMICALS, INC. (JP) | 2006-04-11 | — | — | US | disclosed |
| US-20040030144-A1 | Optically active amine derivative and method of synthesis | MITSUI CHEMICALS, INC. (JP) | 2004-02-12 | — | — | US | disclosed |
| EP-1340743-A1 | OPTICALLY ACTIVE AMINE DERIVATIVE AND METHOD OF SYNTHESIS | Mitsui Chemicals, Inc. (JP) | 2003-09-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040030144-A1 | Optically active amine derivative and method of synthesis | ALDH7A1, AADAT, KMO | USP2 4219/4885L3MBTL1 3437/4885MEN1 1560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.