Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | OGG1 | O15527 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5898567 | 0.83 | ALDH1A1 (0.38) | SMN1; SMN2OGG1MEN1KMT2AALDH1A1 | |
| SCHEMBL8358159 | 0.83 | MAPT (0.45) | MEN1KMT2AALDH1A1TSHRPOLB | |
| SCHEMBL8363409 | 0.83 | KCNN4 (0.52) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL5898588 | 0.82 | MAPT (0.46) | SMN1; SMN2KMT2AKIF11 | |
| SCHEMBL1056429 | 0.81 | ALDH1A1 (0.44) | SMN1; SMN2OGG1ALDH1A1TP53TSHR | |
| SCHEMBL5898550 | 0.79 | KMT2A (0.46) | SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL15066878 | 0.77 | SMN1; SMN2 (0.43) | SMN1; SMN2OGG1MEN1KMT2AALDH1A1 | |
| SCHEMBL23893792 | 0.76 | ALDH1A1 (0.41) | OGG1ALDH1A1TP53TSHRHDAC3 | |
| SCHEMBL5898527 | 0.76 | TSHR (0.39) | SMN1; SMN2MEN1KMT2ATSHRHDAC3 | |
| SCHEMBL5898573 | 0.75 | OGG1 (0.41) | SMN1; SMN2OGG1MEN1KMT2AHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060287397-A1 | Dl-hydroxy-alkyl-phenylamides having anticonvulsive activity | MEZA TOLEDO SERGIO E | 2006-12-21 | — | — | US | disclosed |
| US-20060287397-A1 | Dl-hydroxy-alkyl-phenylamides having anticonvulsive activity | MEZA TOLEDO SERGIO E | 2006-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060287397-A1 | Dl-hydroxy-alkyl-phenylamides having anticonvulsive activity | GABRB2, HRH3, HRH4 | SMN1; SMN2 2748/4885OGG1 4127/4885MEN1 4680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.