Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5898754 | 1.00 | RAB9A (0.34) | RAB9ACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL7100838 | 0.83 | MEN1 (0.37) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL7100840 | 0.83 | MEN1 (0.37) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL1698508 | 0.76 | PIK3CD (0.35) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL1289923 | 0.73 | RAB9A (0.39) | RAB9ACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL3725271 | 0.70 | LMNA (0.49) | RAB9ACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL628286 | 0.70 | LMNA (0.49) | RAB9ACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL15106072 | 0.69 | LMNA (0.44) | RAB9ACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL8331968 | 0.69 | LMNA (0.44) | RAB9ACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL15623779 | 0.69 | RAB9A (0.41) | RAB9ACHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060069091-A9 | Oxazinones and methods for their use and synthesis | CHIROLOGIX PHARMACEUTICALS, INC. | 2006-03-30 | — | — | US | disclosed |
| US-20050124612-A1 | Oxazinones and methods for their use and synthesis | CHIROLOGIX PHARMACEUTICALS, INC. | 2005-06-09 | — | — | US | disclosed |
| US-6861416-B2 | Oxazinones and methods for their use and synthesis | CHIROLOGIX PHARMACEUTICALS, INC. (CA) | 2005-03-01 | — | — | US | disclosed |
| US-20040023956-A1 | New intermediates and synthetic methods for the stereospecific synthesis of oxazinone compounds, which are useful, for example, as antibiotics. The invention also pertains to novel olefinic oxazinone compounds, methods for | CHIROLOGIX PHARMACEUTICALS, INC (CA) | 2004-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060069091-A9 | Oxazinones and methods for their use and synthesis | DHPS, COASY, SQLE | RAB9A 4379/4885CHRM2 4546/4885CHRM4 3553/4885 |
| US-20050124612-A1 | Oxazinones and methods for their use and synthesis | DHPS, COASY, SQLE | RAB9A 4379/4885CHRM2 4546/4885CHRM4 3553/4885 |
| US-20040023956-A1 | New intermediates and synthetic methods for the stereospecific synthesis of oxazinone compounds, which are useful, for example, as antibiotics. The invention also pertains to novel olefinic oxazinone compounds, methods for | SQLE, DHPS, COASY | RAB9A 4250/4885CHRM2 4550/4885CHRM4 3696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.