SCHEMBL5899210

SCHEMBL5899210

Nc1cc(Br)ccc1-c1ccc(Br)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 1/20 0.47
ALDH1A1 P00352 6/20 0.42
MAPK1 P28482 2/20 0.42
ALOX15 P16050 1/20 0.42
ALOX5AP P20292 1/20 0.40
FEN1 P39748 1/20 0.40
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
USP2 O75604 1/20 0.39
S100A4 P26447 1/20 0.39
MAPT P10636 3/20 0.39
APP P05067 1/20 0.39
BCHE P06276 1/20 0.39
ACHE P22303 1/20 0.39
GSK3B P49841 1/20 0.39
CYP2A6 P11509 1/20 0.38
KDM4E B2RXH2 2/20 0.38
GLA P06280 1/20 0.38
PLK4 O00444 1/20 0.37
AURKA O14965 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31183015 1.00 GPR35 (0.47) GPR35ALDH1A1MAPK1ALOX15ALOX5AP
SCHEMBL14906927 0.98 GPR35 (0.48) GPR35ALDH1A1MAPK1ALOX15ALOX5AP
SCHEMBL23579060 0.87 GPR35 (0.42) GPR35ALDH1A1ALOX15MEN1KMT2A
SCHEMBL28593266 0.87 USP7 (0.47) GPR35ALOX15MEN1KMT2AS100A4
SCHEMBL23609324 0.87 GPR35 (0.42) GPR35ALDH1A1MAPK1ALOX15ALOX5AP
SCHEMBL1027801 0.86 ALDH1A1 (0.54) GPR35ALDH1A1MAPK1MAPTACHE
SCHEMBL6011390 0.86 ALDH1A1 (0.50) GPR35ALDH1A1MAPK1ALOX15ALOX5AP
SCHEMBL2841295 0.85 GPR35 (0.59) GPR35ALDH1A1MAPK1ALOX15MEN1
SCHEMBL27412108 0.80 AHR (0.50) GPR35ALDH1A1MAPK1MEN1KMT2A
SCHEMBL23579150 0.78 GPR35 (0.36) GPR35ALOX5APFEN1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109665937-B Synthetic method of 2, 7-dibromo-benzo [9,10] phenanthrene 山东瑞辰新材料有限公司 2021-03-23 CN claimed
CN-109665937-A The synthetic method of 2,7- of one kind bis- bromo- benzo [9,10] phenanthrene 山东瑞辰新材料有限公司 2019-04-23 CN claimed
EP-3877373-B1 5,6-DIPHENYL-5,6-DIHYDRO-DIBENZ[C,E][1,2]AZAPHOSPHORINE AND 6-PHENYL-6H-DIBENZO[C,E][1,2]THIAZINE-5,5-DIOXIDE DERIVATIVES AND RELATED COMPOUNDS AS ORGANIC ELECTROLUMINESCENT MATERIALS FOR OLEDS MERCK PATENT GMBH (DE) 2023-01-11 EP disclosed
US-20220020934-A1 5,6-DIPHENYL-5,6-DIHYDRO-DIBENZ[C,E][1,2]AZAPHOSPHORIN AND 6-PHENYL-6H-DIBENZO[C,E][1,2]THIAZIN-5,5-DIOXIDE DERIVATIVES AND SIMILAR COMPOUNDS AS ORGANIC ELECTROLUMINESCENT MATERIALS FOR OLEDS MERCK PATENT GMBH (DE) 2022-01-20 US disclosed
CN-109665937-B Synthetic method of 2, 7-dibromo-benzo [9,10] phenanthrene 山东瑞辰新材料有限公司 2021-03-23 CN disclosed
CN-109665937-A The synthetic method of 2,7- of one kind bis- bromo- benzo [9,10] phenanthrene 山东瑞辰新材料有限公司 2019-04-23 CN disclosed
US-10038147-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-07-31 US disclosed
US-20150364698-A1 ORGANIC LIGHT-EMITTING DEVICE INDUSTRY-ACADEMIC COOPERATION FOUNDATION GYEONGSANG NATIONAL UNIVERSITY (KR) 2015-12-17 US disclosed
US-20150364698-A1 ORGANIC LIGHT-EMITTING DEVICE INDUSTRY-ACADEMIC COOPERATION FOUNDATION GYEONGSANG NATIONAL UNIVERSITY (KR) 2015-12-17 US disclosed
US-7098297-B2 Electroluminescent polymers and use thereof in light-emitting devices SRI INTERNATIONAL (US) 2006-08-29 US disclosed
EP-1401916-A4 ELECTROLUMINESCENT POLYMERS AND USE THEREOF IN LIGHT-EMITTING DEVICES STANFORD RES INST INT (US) 2005-04-27 EP disclosed
US-20050033015-A1 Electroluminescent polymers and use thereof in light-emitting devices NAVY, SECRETARY OF THE UNITED STATE OF AMERICA OFFICE OF NAVAL RESEARCH 2005-02-10 US disclosed
US-6800722-B2 AROMATIC RESINS WITH PENDANT AMINE GROUPS, FOR EXAMPLE, POLY(2-DIPHENYLAMINO-1,1'-BIPHENYL-4,4'-DIYL); USEFUL AS SEMICONDUCTIVE MATERIALS IN ELECTROLUMINESCENCE DEVICES; SOLUBILITY, CHEMICAL RESISTANCE, HEAT RESISTANCE SRI INTERNATIONAL 2004-10-05 US disclosed
US-6723828-B2 POLYPARAPHENYLENE POLYMERS AND COPOLYMERS WITH POLYTHIOPHENES SRI INTERNATIONAL 2004-04-20 US disclosed
EP-1401916-A1 ELECTROLUMINESCENT POLYMERS AND USE THEREOF IN LIGHT-EMITTING DEVICES SRI INTERNATIONAL (US) 2004-03-31 EP disclosed
US-20030013843-A1 Electroluminescent polymers and use thereof in light-emitting devices NAVY, SECRETARY OF THE, UNITED STATES OF AMERICA 2003-01-16 US disclosed
US-20020193551-A1 Conjugated electroluminescent polymers and associated methods of preparation and use NAVY, UNITED STATES OF AMERICA, SECRETARY OF 2002-12-19 US disclosed
WO-2002094910-A1 ELECTROLUMINESCENT POLYMERS AND USE THEREOF IN LIGHT-EMITTING DEVICES SRI INTERNATIONAL (US) 2002-11-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220020934-A1 5,6-DIPHENYL-5,6-DIHYDRO-DIBENZ[C,E][1,2]AZAPHOSPHORIN AND 6-PHENYL-6H-DIBENZO[C,E][1,2]THIAZIN-5,5-DIOXIDE DERIVATIVES AND SIMILAR COMPOUNDS AS ORGANIC ELECTROLUMINESCENT MATERIALS FOR OLEDS AZI2, OCIAD2, SELP GPR35 2048/4885ALDH1A1 1049/4885MAPK1 3404/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.