SCHEMBL2841295

SCHEMBL2841295

Nc1cc(Br)ccc1-c1ccc(Br)cc1N

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 2/20 0.59
S100A4 P26447 1/20 0.46
ALDH1A1 P00352 3/20 0.44
KDM4E B2RXH2 2/20 0.44
MAPT P10636 2/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
ALOX15 P16050 1/20 0.43
MAPK1 P28482 1/20 0.43
GLA P06280 1/20 0.43
PABPC1 P11940 1/20 0.41
IDO1 P14902 1/20 0.39
BACE1 P56817 2/20 0.39
PTPRC P08575 1/20 0.39
CYP2A6 P11509 1/20 0.39
BCL2 P10415 1/20 0.38
MCL1 Q07820 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA4 P22748 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11728230 0.88 ALDH1A1 (0.59) GPR35S100A4ALDH1A1KDM4EMAPT
SCHEMBL14906927 0.87 GPR35 (0.48) GPR35S100A4ALDH1A1KDM4EMAPT
SCHEMBL22884435 0.86 ALDH1A1 (0.50) GPR35S100A4ALDH1A1KDM4EMAPT
SCHEMBL22201927 0.86 GPR35 (0.49) GPR35S100A4ALDH1A1KDM4EMAPT
SCHEMBL31183015 0.85 GPR35 (0.47) GPR35S100A4ALDH1A1KDM4EMAPT
SCHEMBL5899210 0.85 GPR35 (0.47) GPR35S100A4ALDH1A1KDM4EMAPT
Hydrogen Sulfide SCHEMBL9671090 0.82 GPR35 (0.46) GPR35S100A4ALDH1A1MAPTMEN1
SCHEMBL1027801 0.81 ALDH1A1 (0.54) GPR35ALDH1A1KDM4EMAPTMAPK1
SCHEMBL24206027 0.81 ALDH1A1 (0.48) GPR35S100A4ALDH1A1MAPTMAPK1
SCHEMBL15989743 0.81 TSHR (0.48) GPR35ALDH1A1KDM4EALOX15MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4549472-A2 COMPOSITIONS FOR SUNSCREEN COMPOUNDS AND METHODS THEREOF PMIDG, LLC (US) 2025-05-07 EP disclosed
EP-4013374-B1 COMPOSITIONS FOR SUNSCREEN COMPOUNDS AND METHODS THEREOF PMIDG LLC (US) 2025-02-19 EP disclosed
US-12179173-B2 Functionalized porous organic polymers as uranium nano-traps for efficient uranium extraction UNIVERSITY OF SOUTH FLORIDA (US) 2024-12-31 US disclosed
US-20240109051-A1 FUNCTIONALIZED POROUS ORGANIC POLYMERS AS URANIUM NANO-TRAPS FOR EFFICIENT URANIUM EXTRACTION UNITED STATES DEPARTMENT OF ENERGY 2024-04-04 US disclosed
CN-111867989-B Functionalized porous organic polymers as uranium nanotraps for efficient uranium extraction 南佛罗里达大学 2023-09-26 CN disclosed
US-11628419-B2 Functionalized porous organic polymers as uranium nano-traps for efficient uranium extraction UNIVERSITY OF SOUTH FLORIDA (US) 2023-04-18 US disclosed
US-20220296485-A1 COMPOSITIONS FOR SUNSCREEN COMPOUNDS AND METHODS THEREOF PMIDG, LLC 2022-09-22 US disclosed
EP-4013374-A1 COMPOSITIONS FOR SUNSCREEN COMPOUNDS AND METHODS THEREOF PMIDG, LLC (US) 2022-06-22 EP disclosed
US-11183648-B2 Polymers, their preparation and uses CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2021-11-23 US disclosed
US-11183648-B2 Polymers, their preparation and uses CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2021-11-23 US disclosed
US-20050225235-A1 Materials for injecting or transporting holes and organic electroluminescence devices using the same LG CHEM, LTD. (KR) 2005-10-13 US disclosed
WO-2005090512-A1 NEW MATERIALS FOR INJECTING OR TRANSPORTING HOLES AND ORGANIC ELECTROLUMINESCENCE DEVICES USING THE SAME LG CHEM, LTD. (KR) 2005-09-29 WO disclosed
US-20050119491-A1 2, 7-Substituted carbazoles and oligomers, polymers and co-polymers thereof SHEFFIELD, THE UNIVERSITY OF (GB) 2005-06-02 US disclosed
WO-2005047363-A1 DIBENZOSILOL POLYMERS, THEIR PREPARATION AND USES CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2005-05-26 WO disclosed
EP-0831813-B1 METHODS OF INHIBITING PNEUMOCYSTIS CARINII PNEUMONIA AND COMPOUNDS USEFUL THEREFOR UNIV NORTH CAROLINA (US) 2005-01-19 EP disclosed
EP-0831811-B1 CARBAZOLES FOR TREATING MICROBIAL INFECTIONS UNIV NORTH CAROLINA (US) 2003-11-19 EP disclosed
EP-0831811-A1 METHODS OF TREATING MICROBIAL INFECTIONS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 1998-04-01 EP disclosed
EP-0831813-A1 METHODS OF INHIBITING PNEUMOCYSTIS CARINII PNEUMONIA AND COMPOUNDS USEFUL THEREFOR THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 1998-04-01 EP disclosed
WO-1996040114-A1 METHODS OF INHIBITING PNEUMOCYSTIS CARINII PNEUMONIA AND COMPOUNDS USEFUL THEREFOR THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 1996-12-19 WO disclosed
WO-1996040117-A1 METHODS OF TREATING MICROBIAL INFECTIONS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 1996-12-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11183648-B2 Polymers, their preparation and uses PARG, PARP1, PCBP1 GPR35 3619/4885S100A4 3127/4885ALDH1A1 2464/4885
US-20050225235-A1 Materials for injecting or transporting holes and organic electroluminescence devices using the same SLCO4C1, SLC18A3, SLCO2A1 GPR35 3495/4885S100A4 2741/4885ALDH1A1 757/4885
US-20220296485-A1 COMPOSITIONS FOR SUNSCREEN COMPOUNDS AND METHODS THEREOF NQO1, XPA, ERCC1 GPR35 3302/4885S100A4 562/4885ALDH1A1 186/4885
US-20050119491-A1 2, 7-Substituted carbazoles and oligomers, polymers and co-polymers thereof CBR3, OR10J3, ORC3 GPR35 960/4885S100A4 2785/4885ALDH1A1 2970/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.