SCHEMBL5899549

SCHEMBL5899549

C=CC(=O)Oc1ccc(C(C)(C)c2ccc(OC)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.49
TGM2 P21980 1/20 0.46
MAPT P10636 3/20 0.45
LMNA P02545 2/20 0.44
MAPK1 P28482 2/20 0.44
HSD17B10 Q99714 2/20 0.44
ALDH1A1 P00352 2/20 0.44
ALOX15 P16050 1/20 0.44
APEX1 P27695 1/20 0.44
RECQL P46063 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
PKM P14618 1/20 0.43
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
MAOB P27338 2/20 0.40
NPSR1 Q6W5P4 1/20 0.40
CES2 O00748 1/20 0.40
CES1 P23141 1/20 0.40
TRPV1 Q8NER1 1/20 0.40
RAB9A P51151 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL202339 0.93 THRB (0.54) THRBMAPTHSD17B10ALDH1A1TDP1
SCHEMBL2584694 0.93 THRB (0.54) THRBMAPTHSD17B10ALDH1A1TDP1
SCHEMBL15803539 0.88 THRB (0.50) THRBMAPTHSD17B10ALDH1A1TDP1
SCHEMBL15803521 0.88 THRB (0.50) THRBMAPTHSD17B10ALDH1A1TDP1
SCHEMBL1061204 0.88 THRB (0.59) THRBTGM2MAPTLMNAALDH1A1
SCHEMBL5899677 0.87 THRB (0.49) THRBMAPTLMNAHSD17B10ALDH1A1
SCHEMBL813584 0.87 KDM4E (0.51) THRBMAPTLMNAALDH1A1TDP1
SCHEMBL644250 0.87 ESR1 (0.53) THRBMAPTLMNAHSD17B10ALDH1A1
SCHEMBL16488504 0.87 THRB (0.49) THRBTGM2MAPTLMNAALDH1A1
SCHEMBL27421356 0.84 MAPT (0.44) THRBTGM2MAPTALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060261318-A1 Light control film SUMITOMO CHEMICAL COMPANY, LIMITED 2006-11-23 US disclosed