Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | AR | P10275 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | HTR6 | P50406 | 1/20 | 0.53 |
| ▸ | ESRRG | P62508 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | ELANE | P08246 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL202339 | 0.93 | THRB (0.54) | ESR1ESR2CYP3A4ARHPGD | |
| SCHEMBL2584694 | 0.93 | THRB (0.54) | ESR1ESR2CYP3A4ARHPGD | |
| SCHEMBL3282012 | 0.90 | ESR1 (0.43) | ESR1ESR2CYP3A4ARHPGD | |
| SCHEMBL15803539 | 0.88 | THRB (0.50) | ESR1ESR2CYP3A4ARHPGD | |
| SCHEMBL15803521 | 0.88 | THRB (0.50) | ESR1ESR2CYP3A4ARHPGD | |
| SCHEMBL16488504 | 0.87 | THRB (0.49) | THRBALDH1A1ELANELMNAKDM4E | |
| SCHEMBL5899549 | 0.87 | THRB (0.49) | HSD17B10THRBALDH1A1LMNAKDM4E | |
| SCHEMBL813584 | 0.87 | KDM4E (0.51) | ESR1ESR2CYP3A4THRBALDH1A1 | |
| SCHEMBL5899677 | 0.87 | THRB (0.49) | CYP3A4HSD17B10THRBALDH1A1ELANE | |
| SCHEMBL140760 | 0.86 | THRB (0.56) | ESR1ESR2THRBELANETYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0102199-B2 | Dental restorative compositions having improved mechanical properties and hydrolytic stability | DENTSPLY RES & DEV (US) | 1996-06-12 | — | — | EP | claimed |
| EP-0222059-B1 | IMPROVED RADIATION-HARDENABLE DILUENTS | HENKEL CORPORATION (a Delaware corp.) (US) | 1992-07-08 | — | — | EP | claimed |
| US-5110889-A | Lower alkyl ether acrylates of polyols; coatings | DIAMOND SHAMROCK CHEMICAL CO. (US) | 1992-05-05 | — | — | US | claimed |
| EP-0222059-A2 | Improved radiation-hardenable diluents | HENKEL CORPORATION (a Delaware corp.) (US) | 1987-05-20 | — | — | EP | claimed |
| EP-0102199-B1 | DENTAL RESTORATIVE COMPOSITIONS HAVING IMPROVED MECHANICAL PROPERTIES AND HYDROLYTIC STABILITY | DENTSPLY RESEARCH & DEVELOPMENT CORP. (US) | 1987-02-04 | — | — | EP | claimed |
| EP-1416902-B1 | HARDENABLE SELF-SUPPORTING STRUCTURES AND METHODS | 3M INNOVATIVE PROPERTIES CO (US) | 2014-09-24 | — | — | EP | disclosed |
| US-8436103-B2 | Star polymer and method of producing the same | NIPPON SODA CO., LTD. (JP) | 2013-05-07 | — | — | US | disclosed |
| US-8436103-B2 | Star polymer and method of producing the same | NIPPON SODA CO., LTD. (JP) | 2013-05-07 | — | — | US | disclosed |
| EP-2341510-B1 | Blockcopolymer solid electrolyte, ion-conductive membrane and process for producing the blockcopolymer | NIPPON SODA CO (JP) | 2012-10-31 | — | — | EP | disclosed |
| US-20120077085-A1 | POSITIVE ELECTRODE FOR NON-AQUEOUS ELECTROLYTE BATTERYAND NON-AQUEOUS ELECTROLYTE BATTERY | SAKITANI NOBUHIRO (JP) | 2012-03-29 | — | — | US | disclosed |
| US-20120077085-A1 | POSITIVE ELECTRODE FOR NON-AQUEOUS ELECTROLYTE BATTERYAND NON-AQUEOUS ELECTROLYTE BATTERY | SAKITANI NOBUHIRO (JP) | 2012-03-29 | — | — | US | disclosed |
| US-8142929-B2 | Positive electrode for non-aqueous electrolyte battery and non-aqueous electrolyte battery | SANYO ELECTRIC CO., LTD. (JP) | 2012-03-27 | — | — | US | disclosed |
| US-5159119-A | Monomethyl ether of trans 1,4-cyclohexanedimethylol | DIAMOND SHAMROCK CHEMICALS COMPANY (US) | 1992-10-27 | — | — | US | disclosed |
| EP-0222059-B1 | IMPROVED RADIATION-HARDENABLE DILUENTS | HENKEL CORPORATION (a Delaware corp.) (US) | 1992-07-08 | — | — | EP | disclosed |
| US-5110889-A | Lower alkyl ether acrylates of polyols; coatings | DIAMOND SHAMROCK CHEMICAL CO. (US) | 1992-05-05 | — | — | US | disclosed |
| EP-0266513-B1 | MODIFIED REACTIVE RESIN, PROCESS FOR ITS PREPARATION AND ITS USE | hanse chemie GmbH (DE) | 1991-12-04 | — | — | EP | disclosed |
| US-5053554-A | Monomethyl ether of an ethoxylated or propoxylated(2 average) neopentyl glycol; nonvolatile coating formulation; fact cure; low viscosity; shrinkage inhibition; rheology | DIAMOND SHAMROCK CHEMICAL COMPANY | 1991-10-01 | — | — | US | disclosed |
| US-4876384-A | ALKYL ETHER ACRYLATES AND METHACRYLATES OF ALKOXYLATED AND NONALKOXYLATED POLYOLS; LOW VISCOSITY; SHRINKAGE INHIBITION | DIAMOND SHAMROCK CHEMICALS CO. (US) | 1989-10-24 | — | — | US | disclosed |
| EP-0266513-A2 | Modified reactive resin, process for its preparation and its use | hanse chemie GmbH (DE) | 1988-05-11 | — | — | EP | disclosed |
| EP-0222059-A2 | Improved radiation-hardenable diluents | HENKEL CORPORATION (a Delaware corp.) (US) | 1987-05-20 | — | — | EP | disclosed |