SCHEMBL5899648

SCHEMBL5899648

C=C(Oc1ccc(C(C)(C)c2ccccc2)cc1)C(=O)OCC

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.46
MAPT P10636 2/20 0.46
KDM4E B2RXH2 8/20 0.45
POLB P06746 2/20 0.45
MEN1 O00255 4/20 0.44
KMT2A Q03164 4/20 0.44
HTT P42858 2/20 0.44
SMN1; SMN2 Q16637 5/20 0.43
GAA P10253 2/20 0.43
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
TDP1 Q9NUW8 2/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
LMNA P02545 2/20 0.41
BCHE P06276 1/20 0.41
CHRM2 P08172 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3138875 0.86 KDM4E (0.48) ALDH1A1MAPTKDM4EPOLBMEN1
SCHEMBL134190 0.85 MAPT (0.56) ALDH1A1MAPTKDM4EMEN1KMT2A
SCHEMBL1043461 0.82 MAPT (0.50) ALDH1A1MAPTKDM4EMEN1KMT2A
SCHEMBL12650534 0.82 KDM4E (0.49) ALDH1A1MAPTKDM4EPOLBMEN1
Biphenyl SCHEMBL29274369 0.81 MAPT (0.51) ALDH1A1MAPTKDM4EMEN1KMT2A
SCHEMBL28211319 0.80 KDM4E (0.47) ALDH1A1MAPTKDM4EPOLBMEN1
SCHEMBL22773496 0.80 ELANE (0.61) ALDH1A1MAPTKDM4EMEN1KMT2A
SCHEMBL21841081 0.80 ALDH1A1 (0.50) ALDH1A1MAPTPOLBMEN1KMT2A
SCHEMBL28293864 0.79 CES2 (0.48) ALDH1A1MAPTKDM4EPOLBMEN1
SCHEMBL11672976 0.79 LMNA (0.50) ALDH1A1MAPTKDM4EPOLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117777349-A Organosilicon modified acrylic polyurethane prepolymer, optical adhesive composition, optical adhesive tape, and preparation method and application thereof 东莞市派乐玛新材料技术开发有限公司 2024-03-29 CN claimed
CN-109749634-B Rapid encapsulating tablet based on photocuring and preparation method and application thereof 暨南大学 2021-07-23 CN claimed
US-20060261318-A1 Light control film SUMITOMO CHEMICAL COMPANY, LIMITED 2006-11-23 US claimed
CN-117940488-A Resin composition, adhesive for electronic component, cured product thereof, and electronic component 纳美仕有限公司 2024-04-26 CN disclosed
CN-117777349-A Organosilicon modified acrylic polyurethane prepolymer, optical adhesive composition, optical adhesive tape, and preparation method and application thereof 东莞市派乐玛新材料技术开发有限公司 2024-03-29 CN disclosed
CN-109749634-B Rapid encapsulating tablet based on photocuring and preparation method and application thereof 暨南大学 2021-07-23 CN disclosed
CN-104181774-A Acrylic resin composition, alignment film formed therefrom, and three-dimensional liquid crystal display DAXIN MATERIALS CORP 2014-12-03 CN disclosed
CN-104177881-A Acrylic resin composition, alignment film formed therefrom, and three-dimensional liquid crystal display DAXIN MATERIALS CORP 2014-12-03 CN disclosed
US-20060261318-A1 Light control film SUMITOMO CHEMICAL COMPANY, LIMITED 2006-11-23 US disclosed