SCHEMBL5902585

SCHEMBL5902585

COC1OC(=O)C(C)(C)C(=O)O1

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33
MAPT P10636 1/20 0.31
HTT P42858 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29259024 0.73
SCHEMBL11526935 0.67 POLB (0.38) MEN1KMT2ANPSR1MAPTHTT
SCHEMBL3825916 0.65 MAPT (0.31) MEN1KMT2AMAPTHTTSMN1; SMN2
SCHEMBL10041138 0.64
SCHEMBL13515254 0.62 TP53 (0.42) MEN1KMT2AMAPTSMN1; SMN2
SCHEMBL9418987 0.62
SCHEMBL1784662 0.62
SCHEMBL9731383 0.58 LMNA (0.31)
SCHEMBL12589512 0.58
SCHEMBL1562353 0.58 TSHR (0.38) HTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118215654-A AHR agonists 伊莱利利公司 2024-06-18 CN disclosed
CN-118063648-A Solid catalyst component for propylene polymerization and propylene polymerization catalyst system 中国石油天然气股份有限公司 2024-05-24 CN disclosed
EP-3800185-B1 METHOD FOR MANUFACTURING SALACINOL FUJIFILM CORP (JP) 2024-02-14 EP disclosed
EP-3800185-A1 METHOD FOR MANUFACTURING SALACINOL FUJIFILM Corporation (JP) 2021-04-07 EP disclosed
EP-3521279-B1 METHODS FOR PROTECTING AND DEPROTECTING A DIOL GROUP FUJIFILM CORP (JP) 2021-03-03 EP disclosed
EP-3121170-B1 COMPOUND USEFUL FOR MANUFACTURING SALACINOL, METHOD FOR MANUFACTURING THE COMPOUND, METHOD FOR MANUFACTURING SALACINOL, METHODS FOR PROTECTING AND DEPROTECTING DIOL GROUP, AND PROTECTIVE AGENT FOR DIOL GROUP FUJIFILM CORP (JP) 2019-11-13 EP disclosed
US-10428042-B2 Compound useful for manufacturing salacinol, method for manufacturing the compound, method for manufacturing salacinol, methods for protecting and deprotecting diol group, and protective agent for diol group FUJIFILM CORPORATION (JP) 2019-10-01 US disclosed
EP-3521279-A1 METHODS FOR PROTECTING AND DEPROTECTING A DIOL GROUP Fujifilm Corporation (JP) 2019-08-07 EP disclosed
US-20180327378-A1 COMPOUND USEFUL FOR MANUFACTURING SALACINOL, METHOD FOR MANUFACTURING THE COMPOUND, METHOD FOR MANUFACTURING SALACINOL, METHODS FOR PROTECTING AND DEPROTECTING DIOL GROUP, AND PROTECTIVE AGENT FOR DIOL GROUP FUJIFILM CORPORATION (JP) 2018-11-15 US disclosed
US-10059686-B2 Compound useful for manufacturing salacinol, method for manufacturing the compound, method for manufacturing salacinol, methods for protecting and deprotecting diol group, and protective agent for diol group FUJIFILM CORPORATION (JP) 2018-08-28 US disclosed
US-20030064962-A1 Inhibitors of hepatitis C virus NS3 protease BRISTOL-MYERS SQUIBB COMPANY (FORMERLY D/B/A DUPONT PHARMACEUTICALS COMPANY) 2003-04-03 US disclosed
WO-2002048116-A2 INHIBITORS OF HEPATITIS C VIRUS NS3 PROTEASE BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) 2002-06-20 WO disclosed
EP-0773930-B1 AROMATIC AMINO ETHERS AS PAIN RELIEVING AGENTS ZENECA LTD (GB) 2000-10-11 EP disclosed
EP-0733033-B1 PHARMACEUTICALLY ACTIVE SUBSTITUTED AROMATIC COMPOUNDS ZENECA LTD (GB) 1999-12-22 EP disclosed
US-5843942-A Aromatic amino ethers as pain relieving agents ZENECA LIMITED (GB) 1998-12-01 US disclosed
US-5811459-A PAIN RELIEVERS ZENECA LIMITED (GB) 1998-09-22 US disclosed
EP-0773930-A1 AROMATIC AMINO ETHERS AS PAIN RELIEVING AGENTS ZENECA LIMITED (GB) 1997-05-21 EP disclosed
EP-0733033-A1 PHARMACEUTICALLY ACTIVE SUBSTITUTED AROMATIC COMPOUNDS ZENECA LIMITED (GB) 1996-09-25 EP disclosed
WO-1996011902-A1 PHARMACEUTICALLY ACTIVE SUBSTITUTED AROMATIC COMPOUNDS ZENECA LIMITED (GB) 1996-04-25 WO disclosed
WO-1996003380-A1 AROMATIC AMINO ETHERS AS PAIN RELIEVING AGENTS ZENECA LIMITED (GB) 1996-02-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030064962-A1 Inhibitors of hepatitis C virus NS3 protease PRSS1, SERPINB1, SPINT2 MEN1 3568/4885KMT2A 3760/4885NPSR1 3667/4885
US-10059686-B2 Compound useful for manufacturing salacinol, method for manufacturing the compound, method for manufacturing salacinol, methods for protecting and deprotecting diol group, and protective agent for diol group SPTSSB, ADH1A, DHCR7 MEN1 980/4885KMT2A 1337/4885NPSR1 4394/4885
US-10428042-B2 Compound useful for manufacturing salacinol, method for manufacturing the compound, method for manufacturing salacinol, methods for protecting and deprotecting diol group, and protective agent for diol group SPTSSB, DHCR7, ADH1A MEN1 1012/4885KMT2A 1385/4885NPSR1 4391/4885
US-20180327378-A1 COMPOUND USEFUL FOR MANUFACTURING SALACINOL, METHOD FOR MANUFACTURING THE COMPOUND, METHOD FOR MANUFACTURING SALACINOL, METHODS FOR PROTECTING AND DEPROTECTING DIOL GROUP, AND PROTECTIVE AGENT FOR DIOL GROUP SPTSSB, DHCR7, ADH1A MEN1 1012/4885KMT2A 1385/4885NPSR1 4391/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.