Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOD1 | P00441 | 3/20 | 0.67 |
| ▸ | QPCT | Q16769 | 6/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | GSK3A | P49840 | 1/20 | 0.57 |
| ▸ | GSK3B | P49841 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18457438 | 0.90 | QPCT (0.56) | SOD1QPCTNPC1RAB9AATM | |
| SCHEMBL27418532 | 0.86 | HMOX1 (0.61) | SOD1QPCTNPC1RAB9AATM | |
| SCHEMBL2539814 | 0.86 | SOD1 (0.57) | SOD1QPCTNPC1RAB9AATM | |
| Hydrochloric Acid SCHEMBL5191266 | 0.84 | SOD1 (0.56) | SOD1QPCTNPC1RAB9AATM | |
| SCHEMBL5903394 | 0.83 | NPC1 (0.55) | SOD1QPCTNPC1RAB9AATM | |
| SCHEMBL4138098 | 0.83 | SOD1 (0.54) | SOD1QPCTNPC1RAB9AATM | |
| SCHEMBL5551707 | 0.82 | SOD1 (0.53) | SOD1QPCTNPC1RAB9AATM | |
| SCHEMBL20490589 | 0.81 | QPCT (0.60) | SOD1QPCTNPC1RAB9AATM | |
| SCHEMBL7970502 | 0.80 | QPCT (0.63) | SOD1QPCTNPC1RAB9AATM | |
| SCHEMBL5189230 | 0.80 | QPCT (0.69) | SOD1QPCTNPC1RAB9AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4215220-A | 1-(2-Oxysubstituted-3-anilinopropyl)-imidazoles | CILAG-CHEMIE A.G. (CH) | 1980-07-29 | — | — | US | disclosed |