SCHEMBL590485

SCHEMBL590485

CC(NC(=O)c1cc(Cl)ccc1NC(=O)c1cc(C(F)(F)F)nn1-c1ncccc1Cl)C1CC1

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 3/20 0.42
F10 P00742 6/20 0.39
KLKB1 P03952 6/20 0.39
F9 P00740 1/20 0.39
IDO1 P14902 1/20 0.38
RBP4 P02753 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31438692 0.88 DHODH (0.41) TRPV1F10IDO1RBP4NPC1
SCHEMBL589798 0.88 DHODH (0.41) TRPV1F10IDO1RBP4NPC1
SCHEMBL2293988 0.88 KLKB1 (0.39) TRPV1KLKB1IDO1
SCHEMBL12911867 0.86 TRPV1 (0.45) TRPV1F10F9RBP4
SCHEMBL12911593 0.84 TRPV1 (0.44) TRPV1F10F9RBP4
SCHEMBL950828 0.84 TRPV1 (0.45) TRPV1F10KLKB1F9
SCHEMBL13072905 0.83 TRPV1 (0.43) TRPV1F10F9RBP4
SCHEMBL13104923 0.83 IDO1 (0.39) TRPV1KLKB1IDO1
SCHEMBL13318531 0.82 F10 (0.46) TRPV1F10KLKB1F9
SCHEMBL2958865 0.82 TRPV1 (0.49) TRPV1F10KLKB1F9RBP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104496901-B The manufacture method of anthranilamide compound ISHIHARA SANGYO KAISHA, LTD. (JP) 2016-05-25 CN disclosed
EP-2093223-B1 PROCESS AND INTERMEDIATES FOR PRODUCTION OF AN ANTHRANILAMIDE COMPOUND ISHIHARA SANGYO KAISHA (JP) 2013-08-21 EP disclosed
US-8115006-B2 Process for producing anthranilamide compound ISHIHARA SANGYO KAISHA, LTD. (JP) 2012-02-14 US disclosed
US-20100063293-A1 PROCESS FOR PRODUCING ANTHRANILAMIDE COMPOUND ISHIHARA SANGYO KAISHA ,LTD. (JP) 2010-03-11 US disclosed
EP-2093223-A1 PROCESS FOR PRODUCTION OF ANTHRANILAMIDE COMPOUND ISHIHARA SANGYO KAISHA, LTD. (JP) 2009-08-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100063293-A1 PROCESS FOR PRODUCING ANTHRANILAMIDE COMPOUND NAAA, AAAS, AADAC TRPV1 3266/4885F10 1441/4885KLKB1 4064/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.