Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28475405 | 0.85 | HPGD (0.41) | CYP3A4SLC6A4SLC6A2SLC6A3KIF11 | |
| SCHEMBL19712993 | 0.83 | HTR2C (0.34) | CYP3A4SLC6A4KIF11GABRA1GABRB2 | |
| SCHEMBL624408 | 0.80 | CYP3A4 (0.44) | CYP3A4HPGD | |
| SCHEMBL19712977 | 0.79 | GABRA1 (0.41) | CYP3A4SLC6A4SLC6A2SLC6A3GABRA1 | |
| SCHEMBL484026 | 0.79 | CYP3A4 (0.40) | CYP3A4SLC6A4SLC6A2SLC6A3SMN1; SMN2 | |
| SCHEMBL30568788 | 0.79 | CYP3A4 (0.40) | CYP3A4SLC6A4SLC6A2SLC6A3SMN1; SMN2 | |
| SCHEMBL28481093 | 0.78 | HPGD (0.40) | CYP3A4DHFRSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL10979160 | 0.77 | GABRA1 (0.39) | CYP3A4SLC6A4SLC6A2SLC6A3SMN1; SMN2 | |
| SCHEMBL17847456 | 0.77 | CYP3A4 (0.41) | CYP3A4HPGD | |
| SCHEMBL5905719 | 0.77 | DHFR (0.40) | CYP3A4DHFRSLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060111342-A1 | Insecticidal tricyclic derivatives | BAYER CROPSCIENCE AG (DE) | 2006-05-25 | — | — | US | disclosed |
| EP-1538906-A2 | INSECTICIDAL TRICYCLIC DERIVATIVES | FMC CORPORATION (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004026030-A2 | INSECTICIDAL TRICYCLIC DERIVATIVES | FMC CORPORATION (US) | 2004-04-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060111342-A1 | Insecticidal tricyclic derivatives | DDT, ACHE, ODC1 | CYP3A4 395/4885DHFR 1132/4885SLC6A4 2923/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.