Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 6/20 | 0.53 |
| ▸ | BRD4 | O60885 | 2/20 | 0.47 |
| ▸ | BRD2 | P25440 | 1/20 | 0.47 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.47 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL271730 | 0.82 | MAPK14 (0.68) | MAPK14BRD4BRD2BRD3BRDT | |
| SCHEMBL14324139 | 0.77 | LMNA (0.57) | MAPK14BRD4BRD2BRD3BRDT | |
| SCHEMBL14470357 | 0.77 | MAPK14 (0.51) | MAPK14BRD4BRD2BRD3BRDT | |
| SCHEMBL5907210 | 0.72 | MAPK14 (0.45) | MAPK14SMN1; SMN2MAPTCYP3A4CYP2C19 | |
| 1,2-Diallyloxybenzene SCHEMBL366516 | 0.70 | HPGD (0.60) | MAPTCYP3A4KDM4EALDH1A1LMNA | |
| 1,2-Diallyloxybenzene SCHEMBL29768784 | 0.70 | HPGD (0.60) | MAPTCYP3A4KDM4EALDH1A1LMNA | |
| SCHEMBL12635299 | 0.70 | MAPK1 (0.53) | MAPK14SMN1; SMN2MAPTRAB9AALOX15 | |
| SCHEMBL15804049 | 0.70 | BRD4 (0.54) | MAPK14BRD4BRD2BRD3BRDT | |
| SCHEMBL29001250 | 0.70 | LMNA (0.58) | MAPK14BRD4BRD2BRD3BRDT | |
| 1,2-Diallyloxybenzene SCHEMBL11629869 | 0.70 | TSHR (0.49) | SMN1; SMN2CYP3A4ALOX15KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060106044-A1 | Methods for inhibiting the transmission of HIV using topically applied substituted 6-benzyl-4-oxopyrimidines | IDENIX PHARMACEUTICALS INC. (US) | 2006-05-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060106044-A1 | Methods for inhibiting the transmission of HIV using topically applied substituted 6-benzyl-4-oxopyrimidines | DUT, UNG, NUDT1 | MAPK14 2241/4885BRD4 875/4885BRD2 1537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.