Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5907682 | 0.88 | TAS1R3 (0.45) | POLBKMT2AFAAHMEN1MAPK1 | |
| SCHEMBL5907648 | 0.83 | MMP1 (0.47) | KMT2ASMN1; SMN2ALDH1A1HPGDRAB9A | |
| SCHEMBL8848209 | 0.80 | POLB (0.55) | POLBKMT2ALMNATHRBSMN1; SMN2 | |
| SCHEMBL16298854 | 0.80 | POLB (0.55) | POLBKMT2ALMNATHRBSMN1; SMN2 | |
| SCHEMBL13416265 | 0.80 | POLB (0.55) | POLBKMT2ALMNATHRBSMN1; SMN2 | |
| SCHEMBL8847485 | 0.80 | POLB (0.55) | POLBKMT2ALMNATHRBSMN1; SMN2 | |
| SCHEMBL23179962 | 0.80 | POLB (0.51) | POLBKMT2ALMNATHRBSMN1; SMN2 | |
| SCHEMBL5907667 | 0.80 | POLB (0.42) | POLBKMT2ALMNAALDH1A1TAS1R3 | |
| SCHEMBL5141993 | 0.78 | POLB (0.53) | POLBKMT2ALMNATHRBSMN1; SMN2 | |
| SCHEMBL5143891 | 0.78 | POLB (0.53) | POLBKMT2ALMNATHRBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060046286-A1 | Method for preparing optically active beta-butyrolactones | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2006-03-02 | — | — | US | disclosed |