Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.37 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5907643 | 0.88 | POLB (0.54) | TAS1R3TAS1R1POLBKMT2AFAAH | |
| SCHEMBL15961732 | 0.82 | TAS1R3 (0.49) | TAS1R3TAS1R1TAS1R2POLBKMT2A | |
| SCHEMBL27646624 | 0.80 | GPR84 (0.58) | KMT2AFAAHMEN1MAPK1 | |
| SCHEMBL29148042 | 0.80 | TAS1R3 (0.47) | TAS1R3TAS1R1TAS1R2POLBKMT2A | |
| SCHEMBL5907648 | 0.79 | MMP1 (0.47) | KMT2AMEN1MAPK1 | |
| SCHEMBL23634768 | 0.78 | TAS1R3 (0.46) | TAS1R3TAS1R1TAS1R2POLBKMT2A | |
| SCHEMBL8436643 | 0.78 | TAS1R3 (0.46) | TAS1R3TAS1R1TAS1R2POLBKMT2A | |
| SCHEMBL14370371 | 0.78 | FAAH (0.48) | TAS1R3TAS1R1TAS1R2POLBKMT2A | |
| SCHEMBL5284893 | 0.77 | FAAH (0.69) | KMT2AFAAHMEN1MAPK1CNR2 | |
| SCHEMBL15444589 | 0.76 | FAAH (0.47) | TAS1R3TAS1R1TAS1R2POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060046286-A1 | Method for preparing optically active beta-butyrolactones | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2006-03-02 | — | — | US | disclosed |