Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | CA7 | P43166 | 4/20 | 0.40 |
| ▸ | CA9 | Q16790 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | HTR5A | P47898 | 1/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5908065 | 0.73 | GAA (0.42) | SNCAALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL9117295 | 0.72 | CA1 (0.42) | SNCAALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL10533866 | 0.72 | CA1 (0.42) | ALDH1A1MEN1KMT2ACA1CA2 | |
| SCHEMBL29462816 | 0.72 | RXRA (0.53) | ALDH1A1CA1CA2CA7CA9 | |
| SCHEMBL4420031 | 0.72 | RXRA (0.53) | ALDH1A1CA1CA2CA7CA9 | |
| SCHEMBL23928095 | 0.71 | SNCA (0.50) | SNCAALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL19084279 | 0.71 | CYP1A2 (0.48) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL23960646 | 0.71 | SNCA (0.55) | SNCAALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL3484805 | 0.71 | PDE3B (0.42) | ALDH1A1MEN1KMT2ATSHRCYP3A4 | |
| SCHEMBL29706055 | 0.70 | HTR2C (0.53) | SNCAALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060258652-A1 | Beta-blockers having antioxidant and no-donor activity | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2006-11-16 | — | — | US | disclosed |
| WO-2004047837-A2 | BETA-BLOCKERS HAVING ANTIOXIDANT AND NITRIC OXIDE-DONOR ACTIVITY | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2004-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060258652-A1 | Beta-blockers having antioxidant and no-donor activity | ADRB1, ADRB2, ADRB3 | SNCA 387/4885ALDH1A1 537/4885MEN1 3842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.