SCHEMBL591541

SCHEMBL591541

O=C(c1ccc(OB(O)O)cc1)C(F)(F)F

nearest known ligand 0.50

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CES1 P23141 1/20 0.50
MLYCD O95822 16/20 0.47
TRPV1 Q8NER1 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1938699 0.80 CES1 (0.54) CES1MLYCDTRPV1
SCHEMBL1398393 0.76 CES1 (0.59) CES1MLYCD
SCHEMBL742375 0.75 CA1 (0.56)
SCHEMBL5154503 0.74 CES1 (0.52) CES1MLYCDTRPV1
SCHEMBL5582643 0.74 EPHX2 (0.51) TRPV1
SCHEMBL28690614 0.74 CA1 (0.54)
Ammonia Solution, Strong SCHEMBL31590444 0.74 CA1 (0.54)
SCHEMBL591298 0.74 MAPT (0.61)
SCHEMBL28849890 0.74 ALDH1A1 (0.41) CES1
SCHEMBL3604263 0.74 PARP10 (0.61)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8114956-B2 Polymer having unit obtained by condensation of difluorocyclopentanedione ring and aromatic ring, organic thin film using the same, and organic thin film device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-14 US disclosed