Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.51 |
| ▸ | MLYCD | O95822 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5154503 | 0.86 | CES1 (0.52) | CES1TRPV1MLYCDTLR7 | |
| SCHEMBL24143786 | 0.84 | TRPV1 (0.54) | EPHX2TRPV1NPC1RAB9AFAAH | |
| SCHEMBL9492260 | 0.84 | EPHX2 (0.50) | EPHX2TRPV1NPC1RAB9AFAAH | |
| SCHEMBL20015846 | 0.83 | EPHX2 (0.57) | CES1EPHX2TRPV1NPC1RAB9A | |
| SCHEMBL4475347 | 0.83 | NPC1 (0.60) | EPHX2TRPV1NPC1RAB9AFAAH | |
| SCHEMBL219654 | 0.81 | EPHX2 (0.68) | EPHX2TRPV1NPC1RAB9AFAAH | |
| SCHEMBL26622227 | 0.81 | EPHX2 (0.55) | EPHX2TRPV1NPC1RAB9AFAAH | |
| Hydrochloric Acid SCHEMBL3539826 | 0.81 | NPC1 (0.58) | EPHX2TRPV1NPC1RAB9AFAAH | |
| SCHEMBL7714214 | 0.81 | EPHX2 (0.55) | EPHX2TRPV1NPC1RAB9AFAAH | |
| SCHEMBL591541 | 0.80 | CES1 (0.50) | CES1TRPV1MLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5608062-A | Process for preparing trifluoromethyl ketones | HOECHST SCHERING AGREVO GMBH (DE) | 1997-03-04 | — | — | US | claimed |
| US-20260034094-A1 | COMPOSITIONS AND METHODS FOR INDUCING FERROPTOSIS | KOJIN THERAPEUTICS INC (US) | 2026-02-05 | — | — | US | disclosed |
| US-20250115569-A1 | SULFONAMIDE COMPOUNDS FOR THE TREATMENT OF NEUROLOGICAL CONDITIONS | LARIO THERAPEUTICS LTD (GB) | 2025-04-10 | — | — | US | disclosed |
| EP-4436955-A1 | SULFONAMIDE COMPOUNDS FOR THE TREATMENT OF NEUROLOGICAL CONDITIONS | Lario Therapeutics Limited (GB) | 2024-10-02 | — | — | EP | disclosed |
| WO-2023094830-A1 | SULFONAMIDE COMPOUNDS FOR THE TREATMENT OF NEUROLOGICAL CONDITIONS | LARIO THERAPEUTICS LIMITED (GB) | 2023-06-01 | — | — | WO | disclosed |
| WO-2023094830-A1 | SULFONAMIDE COMPOUNDS FOR THE TREATMENT OF NEUROLOGICAL CONDITIONS | LARIO THERAPEUTICS LIMITED (GB) | 2023-06-01 | — | — | WO | disclosed |
| CN-110862299-B | Method for synthesizing 9-hydroxy-9 trifluoromethyl fluorene compound | 浙江工业大学 | 2022-10-11 | — | — | CN | disclosed |
| CN-110862299-A | Method for synthesizing 9-hydroxy-9 trifluoromethyl fluorene compound | 浙江工业大学 | 2020-03-06 | — | — | CN | disclosed |
| US-10017508-B2 | Nitrogenated heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-07-10 | — | — | US | disclosed |
| EP-2848618-B1 | NITROGENATED HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2018-03-14 | — | — | EP | disclosed |
| EP-0390228-A2 | Chemical intermediates | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-10-03 | — | — | EP | disclosed |
| US-4942264-A | WITTIG REACTION FOLLOWED BY REDUCTION | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-07-17 | — | — | US | disclosed |
| US-4937388-A | Insecticidal ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-06-26 | — | — | US | disclosed |
| US-4891450-A | FLUORINE-CONTAINING ARYLALKENES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-01-02 | — | — | US | disclosed |
| US-4791139-A | Diphenyl ether derivatives and their use as insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-12-13 | — | — | US | disclosed |
| EP-0280383-A1 | Process for intermediates for insecticidal compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-08-31 | — | — | EP | disclosed |
| EP-0279531-A2 | Process and intermediates for the preparation of insecticidally active compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-08-24 | — | — | EP | disclosed |
| EP-0273549-A1 | Insecticidal thioethers and derivatives thereof | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-07-06 | — | — | EP | disclosed |
| EP-0240121-A2 | Diphenyl ether derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-10-07 | — | — | EP | disclosed |
| EP-0211561-A1 | Insecticidal ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-02-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250115569-A1 | SULFONAMIDE COMPOUNDS FOR THE TREATMENT OF NEUROLOGICAL CONDITIONS | CACNA1A, CACNA1E, CACNA1S | CES1 3597/4885EPHX2 4265/4885TRPV1 120/4885 |
| US-20260034094-A1 | COMPOSITIONS AND METHODS FOR INDUCING FERROPTOSIS | AIFM2, GPX4, HMOX1 | CES1 2029/4885EPHX2 1957/4885TRPV1 1730/4885 |
| US-10017508-B2 | Nitrogenated heterocyclic compound | PDE2A, PDE5A, PDE3A | CES1 1285/4885EPHX2 1190/4885TRPV1 2705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.