Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1836944 | 0.78 | TSHR (0.48) | GABRA1TSHRALDH1A1USP2GAA | |
| SCHEMBL5915803 | 0.77 | GABRA1 (0.65) | GABRA1GABRG2GABRB3TSHRHPGD | |
| SCHEMBL11684933 | 0.76 | TSHR (0.40) | TSHRALDH1A1USP2GAAPKM | |
| SCHEMBL5703484 | 0.76 | TSHR (0.40) | TSHRALDH1A1USP2GAAPKM | |
| SCHEMBL5915945 | 0.75 | ALDH1A1 (0.47) | TSHRALDH1A1USP2GAAPKM | |
| SCHEMBL11686432 | 0.74 | ALDH1A1 (0.46) | TSHRALDH1A1USP2GAAPKM | |
| SCHEMBL15065156 | 0.73 | TSHR (0.44) | GABRA1TSHRALDH1A1USP2GAA | |
| SCHEMBL2173625 | 0.73 | TSHR (0.48) | GABRA1TSHRALDH1A1USP2GAA | |
| SCHEMBL6744605 | 0.73 | TSHR (0.44) | GABRA1TSHRALDH1A1USP2GAA | |
| SCHEMBL29402818 | 0.72 | PPARA (0.38) | TSHRALDH1A1USP2GAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060116526-A1 | Process for producing pentaerythritol diphosphonates | TEIJIN CHEMICALS LTD. (JP) | 2006-06-01 | — | — | US | disclosed |
| EP-1586576-A1 | PROCESS FOR THE PRODUCTION OF PENTAERYTHRITOL DIPHOSPHONATES | Teijin Chemicals, Ltd. (JP) | 2005-10-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060116526-A1 | Process for producing pentaerythritol diphosphonates | INPPL1, PHOSPHO1, ARL1 | GABRA1 4245/4885GABRG2 4382/4885GABRB3 4562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.