Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1836944 | 0.81 | TSHR (0.48) | TSHRALOX15HSD17B10USP2ALDH1A1 | |
| SCHEMBL1116090 | 0.79 | USP2 (0.52) | TSHRALOX15HSD17B10USP2ALDH1A1 | |
| SCHEMBL23682242 | 0.79 | USP2 (0.52) | TSHRALOX15HSD17B10USP2ALDH1A1 | |
| SCHEMBL487428 | 0.78 | GAA (0.67) | TSHRALOX15HSD17B10USP2ALDH1A1 | |
| SCHEMBL69217 | 0.77 | ALDH1A1 (0.50) | TSHRALOX15HSD17B10USP2ALDH1A1 | |
| Methane SCHEMBL27627258 | 0.77 | USP2 (0.50) | TSHRALOX15HSD17B10USP2ALDH1A1 | |
| SCHEMBL3399797 | 0.76 | GAA (0.59) | TSHRALOX15HSD17B10USP2ALDH1A1 | |
| SCHEMBL15065156 | 0.76 | TSHR (0.44) | TSHRALOX15HSD17B10USP2ALDH1A1 | |
| SCHEMBL6744605 | 0.76 | TSHR (0.44) | TSHRALOX15HSD17B10USP2ALDH1A1 | |
| SCHEMBL14154101 | 0.76 | GAA (0.59) | TSHRALOX15HSD17B10USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346887-B1 | SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES | DOW TECHNOLOGY INVESTMENTS LLC (US) | 2013-12-25 | — | — | EP | disclosed |
| US-8546600-B2 | Slurry process for synthesis of bisphosphites and situ use thereof for producing bisphosphite | DOW TECHNOLOGY INVESTMENTS LLC | 2013-10-01 | — | — | US | disclosed |
| US-20110196166-A1 | SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES AND SITU USE THEREOF FOR PRODUCING BISPHOSPHITE | DOW TECHNOLOGY INVESTMENTS LLC | 2011-08-11 | — | — | US | disclosed |
| EP-2346887-A1 | SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES | Dow Technology Investments LLC (US) | 2011-07-27 | — | — | EP | disclosed |
| WO-2010042313-A1 | SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES | DOW TECHNOLOGY INVESTMENTS LLC (US) | 2010-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110196166-A1 | SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES AND SITU USE THEREOF FOR PRODUCING BISPHOSPHITE | SOST, PLCB3, PPIP5K2 | TSHR 4332/4885ALOX15 2202/4885HSD17B10 3843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.