Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | AGXT | P21549 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL194803 | 0.80 | TSHR (0.57) | TSHRIDO1AGXTALDH1A1SLC6A2 | |
| SCHEMBL11687302 | 0.78 | TSHR (0.55) | TSHRIDO1AGXTALDH1A1SLC6A2 | |
| SCHEMBL27640727 | 0.78 | KDM4E (0.44) | KDM4EPOLBTSHRIDO1AGXT | |
| SCHEMBL5375962 | 0.77 | KDM4E (0.67) | KDM4EPOLBTSHRIDO1AGXT | |
| SCHEMBL6664633 | 0.76 | ALDH1A1 (0.35) | KDM4EPOLBTSHRALDH1A1HIF1A | |
| Bromide SCHEMBL11675628 | 0.76 | TSHR (0.52) | TSHRIDO1AGXTALDH1A1SLC6A2 | |
| SCHEMBL7934188 | 0.76 | TSHR (0.52) | KDM4EPOLBTSHRIDO1AGXT | |
| SCHEMBL31544527 | 0.76 | TSHR (0.43) | KDM4EPOLBTSHRIDO1AGXT | |
| SCHEMBL29705157 | 0.74 | KDM4E (0.62) | KDM4EPOLBTSHRIDO1AGXT | |
| SCHEMBL3549969 | 0.73 | KDM4E (0.67) | KDM4EPOLBTSHRIDO1AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060116526-A1 | Process for producing pentaerythritol diphosphonates | TEIJIN CHEMICALS LTD. (JP) | 2006-06-01 | — | — | US | disclosed |
| EP-1586576-A1 | PROCESS FOR THE PRODUCTION OF PENTAERYTHRITOL DIPHOSPHONATES | Teijin Chemicals, Ltd. (JP) | 2005-10-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060116526-A1 | Process for producing pentaerythritol diphosphonates | INPPL1, PHOSPHO1, ARL1 | KDM4E 3548/4885POLB 1466/4885TSHR 1836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.