Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 1/20 | 0.51 |
| ▸ | CA6 | P23280 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalic Acid SCHEMBL31186323 | 0.91 | ALDH1A1 (0.58) | LMNAALDH1A1CA2CYP3A4KDM4E | |
| Phthalic Acid SCHEMBL8971732 | 0.91 | ALDH1A1 (0.58) | LMNAALDH1A1CA2CYP3A4KDM4E | |
| Salicylic Acid SCHEMBL31121227 | 0.86 | ALDH1A1 (0.59) | LMNAALDH1A1CA2CYP3A4KDM4E | |
| Octisalate SCHEMBL6853192 | 0.83 | LMNA (0.90) | LMNAALDH1A1CA2CYP3A4KDM4E | |
| Octisalate SCHEMBL20395019 | 0.83 | LMNA (0.90) | LMNAALDH1A1CA2CYP3A4KDM4E | |
| Salicylic Acid SCHEMBL6132155 | 0.82 | ALDH1A1 (0.55) | LMNAALDH1A1CA2CYP3A4KDM4E | |
| Salicylic Acid SCHEMBL27397881 | 0.82 | ALDH1A1 (0.55) | LMNAALDH1A1CA2CYP3A4KDM4E | |
| Salicylic Acid SCHEMBL28438551 | 0.82 | ALDH1A1 (0.58) | LMNAALDH1A1CA2KDM4EHPGD | |
| Benzoic Acid SCHEMBL16781761 | 0.82 | ALDH1A1 (0.58) | LMNAALDH1A1CA2CYP3A4KDM4E | |
| 2-Ethylhexanoic Acid SCHEMBL23398208 | 0.81 | CA2 (0.59) | LMNAALDH1A1CA2CYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115087846-A | Sensor calibration and operation | 唯景公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-101132756-B | Personal care composition containing hydrophobically modified polymers | NALCO CO | 2012-07-04 | — | — | CN | disclosed |
| US-20060183832-A1 | Plasticizer for polyester resin | KAO CORPORATION (JP) | 2006-08-17 | — | — | US | disclosed |