SCHEMBL592002

SCHEMBL592002

Cc1ccc(S(=O)(=O)OC2=NN(c3ncccc3Cl)C(C(=O)Nc3c(Br)cc(Cl)cc3C(=O)NCC3CC3)C2)cc1

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 1/20 0.36
ALDH1A1 P00352 2/20 0.34
CHRM1 P11229 3/20 0.34
KCNH2 Q12809 5/20 0.34
MALT1 Q9UDY8 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
HSD11B1 P28845 1/20 0.33
PKM P14618 1/20 0.33
CACNA1I Q9P0X4 1/20 0.33
F10 P00742 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1148499 0.93 P2RX7 (0.36) P2RX7KCNH2F10
SCHEMBL1148239 0.92 P2RX7 (0.35) P2RX7ALDH1A1KCNH2MEN1KMT2A
SCHEMBL591114 0.91 P2RX7 (0.39) P2RX7CHRM1KCNH2MALT1MEN1
SCHEMBL1148382 0.91 SLC6A9 (0.36) P2RX7ALDH1A1KCNH2MALT1CACNA1I
SCHEMBL1147698 0.89 P2RX7 (0.36) P2RX7CHRM1KCNH2MALT1
SCHEMBL1148230 0.89 GPR17 (0.34) P2RX7ALDH1A1KCNH2MEN1KMT2A
SCHEMBL1148415 0.88 MALT1 (0.37) P2RX7CHRM1MALT1MEN1KMT2A
SCHEMBL591460 0.87 MALT1 (0.33) MALT1HSD11B1F10
SCHEMBL1148353 0.87 F10 (0.35) P2RX7KCNH2F10
SCHEMBL1148274 0.86 MALT1 (0.35) P2RX7ALDH1A1CHRM1MALT1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2093223-B1 PROCESS AND INTERMEDIATES FOR PRODUCTION OF AN ANTHRANILAMIDE COMPOUND ISHIHARA SANGYO KAISHA (JP) 2013-08-21 EP disclosed
US-8115006-B2 Process for producing anthranilamide compound ISHIHARA SANGYO KAISHA, LTD. (JP) 2012-02-14 US disclosed
US-20100063293-A1 PROCESS FOR PRODUCING ANTHRANILAMIDE COMPOUND ISHIHARA SANGYO KAISHA ,LTD. (JP) 2010-03-11 US disclosed
EP-2093223-A1 PROCESS FOR PRODUCTION OF ANTHRANILAMIDE COMPOUND ISHIHARA SANGYO KAISHA, LTD. (JP) 2009-08-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100063293-A1 PROCESS FOR PRODUCING ANTHRANILAMIDE COMPOUND NAAA, AAAS, AADAC P2RX7 4653/4885ALDH1A1 993/4885CHRM1 2756/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.