Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.62 |
| ▸ | NPC1 | O15118 | 8/20 | 0.62 |
| ▸ | RAB9A | P51151 | 8/20 | 0.62 |
| ▸ | APP | P05067 | 5/20 | 0.62 |
| ▸ | GLA | P06280 | 4/20 | 0.62 |
| ▸ | GAA | P10253 | 4/20 | 0.62 |
| ▸ | SNCA | P37840 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | RORC | P51449 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7526379 | 0.88 | MAPT (0.49) | MAPTKDM4ENPC1RAB9AAPP | |
| SCHEMBL11062046 | 0.84 | MAPT (0.70) | MAPTKDM4ENPC1RAB9AAPP | |
| SCHEMBL11062078 | 0.84 | MAPT (0.70) | MAPTKDM4ENPC1RAB9AAPP | |
| SCHEMBL12422217 | 0.82 | MAPT (0.81) | MAPTKDM4ENPC1RAB9AAPP | |
| SCHEMBL4600650 | 0.80 | RAB9A (0.58) | MAPTKDM4ENPC1RAB9AAPP | |
| SCHEMBL7531819 | 0.80 | MAPT (0.72) | MAPTKDM4ENPC1RAB9AAPP | |
| SCHEMBL12422096 | 0.78 | APP (0.62) | MAPTKDM4ENPC1RAB9AAPP | |
| SCHEMBL5349180 | 0.77 | MAPT (0.72) | MAPTKDM4ENPC1RAB9AAPP | |
| SCHEMBL492713 | 0.77 | APP (1.00) | MAPTKDM4ENPC1RAB9AAPP | |
| SCHEMBL13453290 | 0.77 | APP (1.00) | MAPTKDM4ENPC1RAB9AAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11150358-B2 | Radiation dosimetry sol or gel and radiation dosimeter comprising same as material for radiation dosimetry | RIKEN (JP) | 2021-10-19 | — | — | US | disclosed |
| US-20200333474-A1 | RADIATION DOSIMETRY SOL OR GEL AND RADIATION DOSIMETER COMPRISING SAME AS MATERIAL FOR RADIATION DOSIMETRY | RIKEN (JP) | 2020-10-22 | — | — | US | disclosed |
| EP-3686632-A1 | RADIATION DOSIMETRY SOL OR GEL AND RADIATION DOSIMETER COMPRISING SAME AS MATERIAL FOR RADIATION DOSIMETRY | Riken (JP) | 2020-07-29 | — | — | EP | disclosed |
| US-20170023681-A1 | PERSONAL AND SELF INDICATING RADIATION ALERT DOSIMETER | NEW YORK UNIVERSITY | 2017-01-26 | — | — | US | disclosed |
| US-9086489-B2 | Personal and area self-indicating instant radiation alert dosimeter | JP LABORATORIES, INC (US) | 2015-07-21 | — | — | US | disclosed |
| US-8872134-B2 | Self indicating radiation alert dosimeter | JP LABORATORIES, INC (US) | 2014-10-28 | — | — | US | disclosed |
| WO-2013014445-A1 | DERIVATIVES OF PHENYL (THIO) UREA DEOXYTHYMIDINE AND USE THEREOF AS ANTIMALARIALS | UNIVERSITY OF DUNDEE (GB) | 2013-01-31 | — | — | WO | disclosed |
| US-20120205591-A1 | SELF INDICATING RADIATION ALERT DOSIMETER | PATEL GORDHABHAI N (US) | 2012-08-16 | — | — | US | disclosed |
| US-20120181453-A1 | PERSONAL AND AREA SELF-INDICATING INSTANT RADIATION ALERT DOSIMETER | JP LABORATORIES INC. | 2012-07-19 | — | — | US | disclosed |
| US-8115182-B1 | Personal and area self-indicating radiation alert dosimeter | JP LABORATORIES INC. | 2012-02-14 | — | — | US | disclosed |
| US-6635489-B2 | Sensitizing the matrix with heteroaromatic compounds, contacting with reduceable metal salts to stain and detecting | INVITROGEN CORPORATION | 2003-10-21 | — | — | US | disclosed |
| EP-1344055-A1 | MATERIALS FOR ENHANCING STAINING OF BIOPOLYMERS IN MATRICES | INVITROGEN CORPORATION (US) | 2003-09-17 | — | — | EP | disclosed |
| WO-2003024967-A2 | INDOLIZINES AS KINASE PROTEIN INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2003-03-27 | — | — | WO | disclosed |
| US-20020137222-A1 | Materials for enhancing staining of biopolymers in matrices | INVITROGEN CORPORATION | 2002-09-26 | — | — | US | disclosed |
| US-6410598-B1 | ALZHEIMER'S DISEASE; CENTRAL NERVOUS SYSTEM DISORDERS | SYNVISTA THERAPEUTICS, INC. | 2002-06-25 | — | — | US | disclosed |
| WO-2002042764-A1 | MATERIALS FOR ENHANCING STAINING OF BIOPOLYMERS IN MATRICES | INVITROGEN CORPORATION (US) | 2002-05-30 | — | — | WO | disclosed |
| US-6362342-B1 | BIOSYNTHESIS; DRUG LIBRARIES | LION BIOSCIENCE AG (DE) | 2002-03-26 | — | — | US | disclosed |
| US-5935927-A | Compositions and methods for stimulating amyloid removal in amyloidogenic diseases using advanced glycosylation endproducts | THE PICOWER INSTITUTE FOR MEDICAL RESEARCH (US) | 1999-08-10 | — | — | US | disclosed |
| EP-0802797-A1 | COMPOSITIONS AND METHODS FOR ADVANCED GLYCOSYLATION ENDPRODUCT-MEDIATED MODULATION OF AMYLOIDOSIS | THE PICOWER INSTITUTE FOR MEDICAL RESEARCH (US) | 1997-10-29 | — | — | EP | disclosed |
| WO-1995020979-A1 | COMPOSITIONS AND METHODS FOR ADVANCED GLYCOSYLATION ENDPRODUCT-MEDIATED MODULATION OF AMYLOIDOSIS | THE PICOWER INSTITUTE FOR MEDICAL RESEARCH (US) | 1995-08-10 | — | — | WO | disclosed |