SCHEMBL5922945

SCHEMBL5922945

Cn1nc(-c2cc(N)c(Cl)cc2F)c(Cl)c1S(C)(=O)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7506362 0.88 PTGS2 (0.30)
SCHEMBL9530417 0.85 RORC (0.31)
SCHEMBL9533344 0.85 SLC34A1 (0.30)
SCHEMBL27343880 0.85
SCHEMBL9530479 0.84
SCHEMBL9530563 0.82 PTGS2 (0.39)
SCHEMBL9696200 0.81 BRD9 (0.30)
SCHEMBL9529718 0.81 PTGS2 (0.32)
SCHEMBL7972198 0.81 NTRK1 (0.34)
SCHEMBL7590435 0.81 LMNA (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060148649-A1 Substituted n-aryl nitrogen heterocycles BAYER CROPSCIENCE GMBH PATENTS AND LICENSING (DE) 2006-07-06 US disclosed
EP-1599465-A1 SUBSTITUTED N-ARYL NITROGEN HETEROCYCLES Bayer CropScience AG (DE) 2005-11-30 EP disclosed
WO-2004074274-A1 SUBSTITUTED N-ARYL NITROGEN HETEROCYCLES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2004-09-02 WO disclosed
EP-0944623-B1 SUBSTITUTED PYRAZOLE-3-YL BENZAZOLES BASF AG (DE) 2004-09-01 EP disclosed
CN-1145626-C Substituted pyrazole-3-yl benzazoles �����ɷ� 2004-04-14 CN disclosed
US-6232470-B1 AGRICULTURE BASF AKTIENGESELLSCHAFT (DE) 2001-05-15 US disclosed
CN-1244865-A Substituted pyrazole-3-yl benzazoles BASF AK (DE) 2000-02-16 CN disclosed
EP-0944623-A2 SUBSTITUTED PYRAZOLE-3-YL BENZAZOLES BASF AKTIENGESELLSCHAFT (DE) 1999-09-29 EP disclosed
WO-1998027090-A2 SUBSTITUTED PYRAZOLE-3-YL BENZAZOLES BASF AKTIENGESELLSCHAFT (DE) 1998-06-25 WO disclosed
EP-0542872-A1 HERBICIDAL SUBSTITUTED ARYL ALKYLSULFONYL PYRAZOLES MONSANTO COMPANY (US) 1993-05-26 EP disclosed
WO-1992002509-A1 HERBICIDAL SUBSTITUTED ARYL ALKYLSULFONYL PYRAZOLES MONSANTO COMPANY (US) 1992-02-20 WO disclosed