Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | UBE2M | P61081 | 9/20 | 0.43 |
| ▸ | DCUN1D1 | Q96GG9 | 9/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | CCR3 | P51677 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5923658 | 0.87 | DRD2 (0.48) | DRD2CCR3 | |
| SCHEMBL5923589 | 0.85 | UBE2M (0.49) | DRD2UBE2MDCUN1D1 | |
| SCHEMBL4769696 | 0.84 | CYP3A4 (0.50) | DRD2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL5923753 | 0.78 | ADRA1D (0.58) | — | |
| SCHEMBL5923679 | 0.78 | DRD2 (0.44) | DRD2 | |
| SCHEMBL5923701 | 0.77 | DRD4 (0.45) | DRD2HDAC1UBE2MDCUN1D1RAB9A | |
| SCHEMBL5923750 | 0.75 | DRD2 (0.56) | DRD2 | |
| SCHEMBL5508600 | 0.75 | DRD2 (0.56) | DRD2 | |
| SCHEMBL4768518 | 0.74 | DRD2 (0.47) | DRD2 | |
| SCHEMBL5521956 | 0.74 | DRD2 (0.53) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060041139-A9 | SUBSTITUTED ALKYL AMIDO PIPERIDINES | H. LUNDBECK A/S (DK) | 2006-02-23 | — | — | US | disclosed |
| US-20040073036-A1 | Substituted alkyl amido piperidines | SYNAPTIC PHARMACEUTICAL CORPORATION | 2004-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040073036-A1 | Substituted alkyl amido piperidines | MCHR1, MCHR2, MC1R | DRD2 74/4885CYP3A4 2068/4885CYP2D6 1637/4885 |
| US-20060041139-A9 | SUBSTITUTED ALKYL AMIDO PIPERIDINES | MCHR1, MCHR2, MC1R | DRD2 74/4885CYP3A4 2068/4885CYP2D6 1637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.