Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIFC1 | Q9BW19 | 2/20 | 0.48 |
| ▸ | GPR34 | Q9UPC5 | 7/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5926899 | 0.94 | ITGA4 (0.42) | KIFC1GPR34ITGB1ITGA4ITGB7 | |
| SCHEMBL5926329 | 0.92 | KIFC1 (0.51) | KIFC1GPR34PTPN1ITGB1ITGA4 | |
| SCHEMBL3991234 | 0.90 | FFAR1 (0.42) | KIFC1GPR34ITGB1ITGA4ITGB7 | |
| SCHEMBL5926738 | 0.90 | SERPINE1 (0.49) | KIFC1GPR34PTPN1GPR132ITGB1 | |
| SCHEMBL5927210 | 0.89 | ITGA4 (0.45) | KIFC1GPR34ITGB1ITGA4ITGB7 | |
| SCHEMBL5926544 | 0.89 | FFAR1 (0.41) | GPR34PLA2G1BHTTL3MBTL1ATG4B | |
| SCHEMBL5926977 | 0.88 | FFAR1 (0.45) | KIFC1GPR34ITGB1ITGA4ITGB7 | |
| SCHEMBL5926282 | 0.86 | GPR34 (0.42) | KIFC1GPR34GPR132ITGB1ITGA4 | |
| SCHEMBL5927129 | 0.86 | GPR34 (0.57) | KIFC1GPR34PTPN1GPR132ITGB1 | |
| SCHEMBL5926825 | 0.85 | ITGB1 (0.40) | KIFC1GPR34ITGB1ITGA4ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060276518-A1 | Aryl and heteroaryl compounds and methods to modulate coagulation | TRANSTECH PHARMA, INC. | 2006-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276518-A1 | Aryl and heteroaryl compounds and methods to modulate coagulation | TFPI, F9, F2 | KIFC1 4489/4885GPR34 4272/4885PTPN1 2517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.