Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 11/20 | 0.50 |
| ▸ | ITGA4 | P13612 | 9/20 | 0.50 |
| ▸ | ITGB7 | P26010 | 5/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.49 |
| ▸ | ITGAV | P06756 | 2/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.49 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.49 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.48 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.47 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.47 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | CPA1 | P15085 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5927087 | 0.85 | CYP26A1 (0.49) | — | |
| SCHEMBL5926900 | 0.83 | ITGB1 (0.47) | ITGB1ITGA4ITGB7ERAP1KMT2A | |
| SCHEMBL5927430 | 0.82 | GPR34 (0.47) | ITGB1ITGA4ITGB7GPR34ERAP1 | |
| SCHEMBL5927021 | 0.82 | KMT2A (0.43) | ITGB1ITGA4ITGB7ITGB3ITGAV | |
| SCHEMBL5927054 | 0.82 | ITGB1 (0.50) | ITGB1ITGA4ITGB7GPR34PDK1 | |
| SCHEMBL5926657 | 0.81 | ERAP1 (0.48) | ITGB1ITGA4ITGB7GPR34PDK1 | |
| SCHEMBL5926244 | 0.80 | GPR34 (0.49) | ITGB1ITGA4ITGB7GPR34PDK1 | |
| SCHEMBL5926995 | 0.80 | PSMB5 (0.62) | ITGB1ITGA4ITGB7GPR34ERAP1 | |
| SCHEMBL5927209 | 0.80 | ITGB1 (0.55) | ITGB1ITGA4ITGB7GPR34PDK1 | |
| SCHEMBL5927210 | 0.80 | ITGA4 (0.45) | ITGB1ITGA4ITGB7GPR34PDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060276518-A1 | Aryl and heteroaryl compounds and methods to modulate coagulation | TRANSTECH PHARMA, INC. | 2006-12-07 | — | — | US | disclosed |
| US-7122580-B2 | Aryl and heteroaryl compounds and methods to modulate coagulation | TRANSTECH PHARMA, INC. (US) | 2006-10-17 | — | — | US | disclosed |
| US-20040110832-A1 | management, treatment and/or control of diseases caused in intrinsic clotting pathway utilizing factor IX such as stroke, myocardial infarction, aneurysm surgery, and deep vein thrombosis associated with surgical procedures etc | TRANSTECH PHARMA, LLC | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110832-A1 | management, treatment and/or control of diseases caused in intrinsic clotting pathway utilizing factor IX such as stroke, myocardial infarction, aneurysm surgery, and deep vein thrombosis associated with surgical procedures etc | TFPI, F9, TFPI2 | ITGB1 139/4885ITGA4 171/4885ITGB7 541/4885 |
| US-20060276518-A1 | Aryl and heteroaryl compounds and methods to modulate coagulation | TFPI, F9, F2 | ITGB1 240/4885ITGA4 312/4885ITGB7 762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.