Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 9/20 | 0.55 |
| ▸ | ITGA4 | P13612 | 9/20 | 0.55 |
| ▸ | ITGB7 | P26010 | 5/20 | 0.53 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.51 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.51 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.51 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.51 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.49 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | PYGL | P06737 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5927213 | 0.82 | CTSA (0.52) | SERPINE1KDM4ENPSR1RXFP1LMNA | |
| SCHEMBL5926657 | 0.82 | ERAP1 (0.48) | ITGB1ITGA4ITGB7PDK1PDK2 | |
| SCHEMBL5927188 | 0.81 | ITGB1 (0.52) | ITGB1ITGA4ITGB7PSMB5GPR34 | |
| SCHEMBL5926755 | 0.80 | KCNA5 (0.60) | ITGB1ITGA4 | |
| SCHEMBL8340240 | 0.80 | KCNA5 (0.60) | ITGB1ITGA4 | |
| SCHEMBL5926619 | 0.80 | ITGA4 (0.47) | ITGB1ITGA4ITGB7SERPINE1NPSR1 | |
| SCHEMBL5926681 | 0.80 | ERAP1 (0.53) | ITGB1ITGA4ITGB7GPR34NHERF1 | |
| SCHEMBL3992010 | 0.80 | PDK1 (0.54) | ITGB1ITGA4ITGB7SERPINE1PDK1 | |
| SCHEMBL5926666 | 0.80 | ITGB1 (0.54) | ITGB1ITGA4ITGB7GPR34NHERF1 | |
| SCHEMBL8337957 | 0.80 | ITGB1 (0.54) | ITGB1ITGA4ITGB7GPR34NHERF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060276518-A1 | Aryl and heteroaryl compounds and methods to modulate coagulation | TRANSTECH PHARMA, INC. | 2006-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276518-A1 | Aryl and heteroaryl compounds and methods to modulate coagulation | TFPI, F9, F2 | ITGB1 240/4885ITGA4 312/4885ITGB7 762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.