Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 4/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.42 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3999747 | 0.94 | KCNQ3 (0.44) | PTPN11GPR88ALDH1A1LMNAMAPK1 | |
| SCHEMBL3995217 | 0.93 | PTPN11 (0.46) | PTPN11GPR88ALDH1A1LMNAMAPK1 | |
| SCHEMBL3991621 | 0.92 | PTPN11 (0.44) | CYP26A1PTPN11GPR88ALDH1A1LMNA | |
| SCHEMBL5926898 | 0.92 | FFAR4 (0.46) | PTPN11GPR88ALDH1A1LMNAMAPK1 | |
| SCHEMBL3995234 | 0.91 | MMP12 (0.48) | PTPN11GPR88ALDH1A1LMNAMAPK1 | |
| SCHEMBL5927443 | 0.88 | LMNA (0.45) | ALDH1A1LMNAMAPK1KCNQ3KCNQ2 | |
| SCHEMBL3996604 | 0.87 | LRRK2 (0.45) | CYP26A1ALDH1A1LMNAMAPK1KCNQ3 | |
| SCHEMBL5926667 | 0.87 | PTPN11 (0.45) | PTPN11GPR88ALDH1A1LMNAMAPK1 | |
| SCHEMBL3998698 | 0.87 | KCNQ3 (0.42) | PTPN11KCNQ3KCNQ2PTGDR2 | |
| SCHEMBL4829602 | 0.87 | ITGA4 (0.44) | PTPN11ALDH1A1LMNAPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060276518-A1 | Aryl and heteroaryl compounds and methods to modulate coagulation | TRANSTECH PHARMA, INC. | 2006-12-07 | — | — | US | disclosed |
| US-7122580-B2 | Aryl and heteroaryl compounds and methods to modulate coagulation | TRANSTECH PHARMA, INC. (US) | 2006-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276518-A1 | Aryl and heteroaryl compounds and methods to modulate coagulation | TFPI, F9, F2 | CYP26A1 526/4885PTPN11 2131/4885GPR88 2355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.