Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Raspberryketone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 2/20 | 0.52 |
| ▸ | ESR2 known ✓ | Q92731 | 1/20 | 0.52 |
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | F13A1 | P00488 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Raspberryketone SCHEMBL43308 | 0.96 | ALDH1A1 (0.65) | ALDH1A1KDM4EF13A1ESR1ESR2 | |
| Raspberryketone SCHEMBL8759829 | 0.92 | ALDH1A1 (0.61) | ALDH1A1KDM4EF13A1ESR1ESR2 | |
| Raspberryketone SCHEMBL1697198 | 0.90 | ALDH1A1 (0.59) | ALDH1A1KDM4EF13A1ESR1ESR2 | |
| Raspberryketone SCHEMBL30530334 | 0.89 | ALDH1A1 (0.58) | ALDH1A1KDM4EF13A1ESR1ESR2 | |
| Hydroxyphenyl Propionic Acid SCHEMBL7727261 | 0.88 | FFAR1 (0.61) | KDM4EF13A1ESR1ESR2LMNA | |
| SCHEMBL10912165 | 0.87 | ALDH1A1 (0.77) | ALDH1A1KDM4EF13A1LMNATP53 | |
| Benzylacetone SCHEMBL27760585 | 0.86 | ALDH1A1 (0.84) | ALDH1A1KDM4ECYP19A1KMT2AMAPT | |
| Raspberryketone SCHEMBL8759844 | 0.85 | ALDH1A1 (0.53) | ALDH1A1KDM4EF13A1ESR1ESR2 | |
| Raspberryketone SCHEMBL28250175 | 0.83 | CALM1 (0.66) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL106915 | 0.83 | ESR1 (0.53) | ALDH1A1KDM4EF13A1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10172342-B2 | Apparatus for pest control | BASF SE (DE) | 2019-01-08 | — | — | US | claimed |
| US-20140366429-A1 | Apparatus for Pest Control | BASF SE (DE) | 2014-12-18 | — | — | US | claimed |
| EP-2244565-B1 | APPARATUS FOR PEST CONTROL | BASF SE (DE) | 2011-08-31 | — | — | EP | claimed |
| US-20100325941-A1 | Apparatus for Pest Control | BASF SE (DE) | 2010-12-30 | — | — | US | claimed |
| EP-2244565-A1 | APPARATUS FOR PEST CONTROL | BASF SE (DE) | 2010-11-03 | — | — | EP | claimed |
| WO-2009092783-A1 | APPARATUS FOR PEST CONTROL | BASF SE (DE) | 2009-07-30 | — | — | WO | claimed |
| US-5750129-A | SOLID RESERVOIRS ENCAPSULATED WITH POROUS MEMBRANE | PHERO TECH INC. (CA) | 1998-05-12 | — | — | US | claimed |
| EP-0730403-A1 | INSECT ATTRACTANT FORMULATION | AGRISENSE- BCS LIMITED (GB) | 1996-09-11 | — | — | EP | claimed |
| WO-1995014379-A1 | INSECT ATTRACTANT FORMULATION | AGRISENSE - BCS LIMITED (GB) | 1995-06-01 | — | — | WO | claimed |
| US-4283878-A | Insect trap | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1981-08-18 | — | — | US | claimed |
| EP-1606334-B1 | POLYAMIDE-POLYETHER BLOCK COPOLYMER | CRODA INT PLC (GB) | 2019-04-03 | — | — | EP | disclosed |
| US-10172342-B2 | Apparatus for pest control | BASF SE (DE) | 2019-01-08 | — | — | US | disclosed |
| EP-2099605-B1 | COMPOSITION AND ARTICLES CONTAINING CROSS-LIINKED POLYMER MATRIX AND IMMOBILIZED ACTIVE LIQUID, AND METHODS OF MAKING SAME | CRODA INT PLC (GB) | 2018-04-18 | — | — | EP | disclosed |
| US-20140366429-A1 | Apparatus for Pest Control | BASF SE (DE) | 2014-12-18 | — | — | US | disclosed |
| US-8664292-B2 | Compositions and articles containing a cross-linked polymer matrix and an immobilized active liquid, as well as methods of making and using the same | CRODA INTERNATIONAL PLC (GB) | 2014-03-04 | — | — | US | disclosed |
| WO-2004083280-A1 | POLYAMIDE-POLYETHER BLOCK COPOLYMER | ARIZONA CHEMICAL COMPANY (US) | 2004-09-30 | — | — | WO | disclosed |
| US-20040186263-A1 | having softening point of 60-180 degrees C, formed from reaction mixture comprising 1,4-cyclohexanedicarboxylic acid and compounds comprising polyalkyleneoxydiamine, reaction mixture containing no monofunctional compound reactive with amine or acid | ARIZONA CHEMICAL COMPANY | 2004-09-23 | — | — | US | disclosed |
| US-5750129-A | SOLID RESERVOIRS ENCAPSULATED WITH POROUS MEMBRANE | PHERO TECH INC. (CA) | 1998-05-12 | — | — | US | disclosed |
| EP-0730403-A1 | INSECT ATTRACTANT FORMULATION | AGRISENSE- BCS LIMITED (GB) | 1996-09-11 | — | — | EP | disclosed |
| WO-1995014379-A1 | INSECT ATTRACTANT FORMULATION | AGRISENSE - BCS LIMITED (GB) | 1995-06-01 | — | — | WO | disclosed |