Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5932139 | 0.98 | TUBB1 (0.41) | TUBB1ALOX5PTGS1PTGS2NPC1 | |
| SCHEMBL17968578 | 0.81 | TRPM8 (0.45) | TUBB1ALOX5PTGS1PTGS2NPC1 | |
| SCHEMBL7536052 | 0.81 | RELA (0.50) | TUBB1PTGS2NPC1RAB9AMAPT | |
| SCHEMBL17968585 | 0.80 | NFE2L2 (0.44) | TUBB1ALOX5PTGS1PTGS2NPC1 | |
| SCHEMBL23244052 | 0.79 | TRPM8 (0.50) | TUBB1ALOX5PTGS1PTGS2NPC1 | |
| SCHEMBL21596594 | 0.79 | TRPM8 (0.50) | TUBB1ALOX5PTGS1PTGS2NPC1 | |
| SCHEMBL1397152 | 0.78 | HSP90AA1 (0.42) | SMN1; SMN2KDM4E | |
| SCHEMBL23244045 | 0.78 | HSP90AA1 (0.42) | SMN1; SMN2KDM4E | |
| SCHEMBL27608173 | 0.75 | CHRNB4 (0.42) | SMN1; SMN2KDM4EMAOBPOLB | |
| SCHEMBL10299699 | 0.73 | HCAR2 (0.47) | ALOX5MAPTLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060188812-A1 | Phenolic hydroxyl group-containing copolymer and radiation-sensitive resin composition | JSR CORPORATION (JP) | 2006-08-24 | — | — | US | disclosed |
| EP-1686424-A2 | Radiation-sensitive resin composition | JSR Corporation (JP) | 2006-08-02 | — | — | EP | disclosed |
| US-20060166138-A1 | Radiation-sensitive resin composition | JSR CORPORATION | 2006-07-27 | — | — | US | disclosed |