SCHEMBL59322

SCHEMBL59322

C#CCCC([CH2])C#CCCCC

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12095321 0.85 HMGCR (0.32)
SCHEMBL61022 0.84 HMGCR (0.37)
SCHEMBL60205 0.84 HMGCR (0.37)
SCHEMBL7554246 0.70 USP2 (0.30)
SCHEMBL2120933 0.70
SCHEMBL6045296 0.69 TSHR (0.39) TSHR
SCHEMBL15272802 0.69 TSHR (0.33) TSHR
SCHEMBL29127582 0.69 ALDH1A1 (0.33) TSHR
SCHEMBL9522800 0.68
SCHEMBL601538 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 697 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4385991-A1 COMPOUND HAVING SHP2 PROTEIN DEGRADING ACTIVITY, AND MEDICAL USES THEREOF Ubix Therapeutics, Inc. (KR) 2024-06-19 EP disclosed
US-20240158439-A1 INHIBITORS OF ANTIGEN PRESENTATION BY MHC CLASS II HLA-DRB1*15:01 MOLECULES WITH ENHANCED METABOLIC STABILITY PROVID PHARMACEUTICALS INC. 2024-05-16 US disclosed
US-11976085-B2 Process for producing ruthenium complexes and intermediates thereof and their use in olefin metathesis Aperion Synthesis S.A. (PL) 2024-05-07 US disclosed
CN-117881678-A Compound with SHP2 protein degradation activity and medical application thereof 尤比克斯治疗公司 2024-04-12 CN disclosed
US-20240076308-A1 PROCESS FOR PRODUCING RUTHENIUM COMPLEXES AND INTERMEDIATES THEREOF AND THEIR USE IN OLEFIN METATHESIS APEIRON SYNTHESIS SA (PL) 2024-03-07 US disclosed
EP-4112053-B1 TREATMENT OF SYNUCLEINOPATHIES DEUTSCHES ZENTRUM FUER NEURODEGENERATIVE ERKRANKUNGEN E V DZNE (DE) 2024-02-14 EP disclosed
EP-4308585-A1 INHIBITORS OF ANTIGEN PRESENTATION BY MHC CLASS II HLA-DRB1*15:01 MOLECULES WITH ENHANCED METABOLIC STABILITY Provid Pharmaceuticals Inc. (US) 2024-01-24 EP disclosed
US-20240018123-A1 COMPOUND FOR INHIBITING OR DISINTEGRATING ANDROGEN RECEPTOR, AND PHARMACEUTICAL USE THEREOF KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2024-01-18 US disclosed
WO-2024005556-A1 Compounds, pharmaceutical compositions containing them and their medical use for the treatment or prevention of vascular diseases VASTHERA CO., LTD. (KR) 2024-01-04 WO disclosed
US-20230286934-A1 Use of Multi-Kinase Inhibitors to Treat RNA Virus Infections ICAHN SCHOOL MED MOUNT SINAI (US) 2023-09-14 US disclosed
WO-2004009610-A2 USE OF NUCLEOSIDE COMPOUNDS FOR NONSENSE SUPPRESSION AND THE TREATMENT OF GENETIC DISEASES PTC THERAPEUTICS, INC. (US) 2004-01-29 WO disclosed
WO-2004009609-A2 NUCLEOSIDE COMPOUNDS AND THEIR USE FOR TREATING CANCER AND DISEASES ASSOCIATED WITH SOMATIC MUTATIONS PTC THERAPEUTICS, INC. (US) 2004-01-29 WO disclosed
WO-2004009563-A1 5-ARYLTETRAZOLE COMPOUNDS, COMPOSITIONS THEREOF, AND USES THEREFOR INOTEK PHARMACEUTICALS CORPORATION (US) 2004-01-29 WO disclosed
WO-2004004774-A2 COMPOSITIONS COMPRISING PANTHETINE FOR THE TREATMENT OF DYSLIPIDEMIA ESPERION THERAPEUTICS, INC. (US) 2004-01-15 WO disclosed
WO-2004002983-A2 THERAPEUTIC PIPERAZINE DERIVATIVES USEFUL FOR TREATING PAIN EURO-CELTIQUE, S.A. (LU) 2004-01-08 WO disclosed
WO-2003105774-A2 COMPOUNDS USEFUL FOR THE TREATMENT OF CANCER, COMPOSITIONS THEREOF AND METHODS THEREWITH SIGNAL PHARMACEUTICALS, INC. (US) 2003-12-24 WO disclosed
WO-2003102151-A2 MODULATING CELL DIFFERENTIATION AND TREATING MYELOPROLIFERTIVE DISORDERS WITH JNK/MKK INHIBITORS CELGENE CORPORATION (US) 2003-12-11 WO disclosed
WO-2003099221-A2 METHODS FOR USING JNK INHIBITORS FOR TREATING OR PREVENTING DISEASE-RELATED WASTING SIGNAL PHARMACEUTICALS, INC. (US) 2003-12-04 WO disclosed
WO-2003093236-A1 1-(PYRID-2-YL)-PIPERAZINE COMPOUNDS AS METABOTROPIC GLUTAMATE RECEPTOR INHIBITOR EURO-CELTIQUE, S.A. (LU) 2003-11-13 WO disclosed
WO-2003075917-A1 COMBINATION THERAPY FOR TREATING, PREVENTING OR MANAGING PROLIFERATIVE DISORDERS AND CANCERS SIGNAL PHARMACEUTICALS, INC. (US) 2003-09-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240158439-A1 INHIBITORS OF ANTIGEN PRESENTATION BY MHC CLASS II HLA-DRB1*15:01 MOLECULES WITH ENHANCED METABOLIC STABILITY HLA-DRB1, HLA-B, HLA-C TSHR 4258/4885
US-11976085-B2 Process for producing ruthenium complexes and intermediates thereof and their use in olefin metathesis POR, CYP1B1, CYP4F11 TSHR 4724/4885
US-20230286934-A1 Use of Multi-Kinase Inhibitors to Treat RNA Virus Infections EIF2AK2, SARS1, ACE2 TSHR 4743/4885
US-20240018123-A1 COMPOUND FOR INHIBITING OR DISINTEGRATING ANDROGEN RECEPTOR, AND PHARMACEUTICAL USE THEREOF AR, NR5A1, SHBG TSHR 1118/4885
US-20240076308-A1 PROCESS FOR PRODUCING RUTHENIUM COMPLEXES AND INTERMEDIATES THEREOF AND THEIR USE IN OLEFIN METATHESIS POR, CYP1B1, CYP4F11 TSHR 4724/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.