SCHEMBL5933367

SCHEMBL5933367

O=C([S])OCc1cccc2ccccc12

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.54
TDP1 Q9NUW8 1/20 0.53
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
PARP10 Q53GL7 1/20 0.51
SLC1A3 P43003 1/20 0.50
SLC1A2 P43004 1/20 0.50
SLC1A1 P43005 1/20 0.50
ATM Q13315 1/20 0.49
FFAR1 O14842 1/20 0.48
AKR1B1 P15121 1/20 0.48
ACP3 P15309 1/20 0.47
CYP1A2 P05177 1/20 0.46
MTNR1A P48039 1/20 0.45
CTNNB1 P35222 1/20 0.45
PPARG P37231 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21372579 0.85 TDP1 (0.56) EPHX1TDP1MEN1KMT2APARP10
SCHEMBL28702056 0.85 TDP1 (0.56) EPHX1TDP1MEN1KMT2APARP10
SCHEMBL2575314 0.84 EPHX1 (0.55) EPHX1TDP1MEN1KMT2APARP10
SCHEMBL2575317 0.84 TDP1 (0.59) EPHX1TDP1MEN1KMT2APARP10
SCHEMBL5077569 0.82 EPHX1 (0.54) EPHX1TDP1MEN1KMT2APARP10
SCHEMBL487420 0.82 KMT2A (0.55) EPHX1TDP1MEN1KMT2APARP10
SCHEMBL5933380 0.82 EPHX1 (0.54) EPHX1TDP1MEN1KMT2APARP10
SCHEMBL1998524 0.82 EPHX1 (0.54) EPHX1TDP1MEN1KMT2APARP10
SCHEMBL1998527 0.82 MEN1 (0.59) EPHX1TDP1MEN1KMT2APARP10
SCHEMBL2639206 0.81 EPHX1 (0.52) EPHX1TDP1MEN1KMT2APARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060088786-A1 Rewritable optical information recording medium, recording and reproducing methods, as well as recording and reproducing apparatus MITSUI CHEMICALS, INC. (JP) 2006-04-27 US disclosed
EP-1484191-A1 REWRITABLE OPTICAL INFORMATION RECORDING MEDIUM AND RECORDING/REPRODUCING METHOD, RECORDING/REPRODUCING DEVICE Sony Corporation (JP) 2004-12-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060088786-A1 Rewritable optical information recording medium, recording and reproducing methods, as well as recording and reproducing apparatus ALPG, TRPC6, GNRHR EPHX1 2778/4885TDP1 316/4885MEN1 1357/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.